{"id":"W4394237221","doi":"10.6084/m9.figshare.21952694","title":"RETRACTED ARTICLE: NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":true,"has_abstract":true,"ca_institutions":"Vector Institute; University of Toronto; University Health Network; Canadian Institute for Advanced Research","funders":"","keywords":"Carcinoembryonic antigen; PI3K/AKT/mTOR pathway; Carboplatin; Protein kinase B; Lung cancer; Cancer research; Chemistry; Cell; Hypoxia (environmental); Cancer; Medicine; Internal medicine; Biochemistry; Signal transduction; Cisplatin; Oxygen; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.008122822,0.001402135,0.00195763,0.003142548,0.003210905,0.0062702,0.003804395,0.0102828,0.05081758],"category_scores_gemma":[0.04398511,0.0007490191,0.002462931,0.002165359,0.002964702,0.003481568,0.003108997,0.008017547,0.03668552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00345711,"about_ca_system_score_gemma":0.005884323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002734182,"about_ca_topic_score_gemma":0.004210453,"domain_scores_codex":[0.9915485,0.0008208149,0.001483177,0.0006757169,0.004755707,0.000716066],"domain_scores_gemma":[0.9707219,0.007457788,0.002440023,0.001568305,0.01588103,0.001930875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001956361,0.00006166533,0.0004880282,0.0006358851,0.0000662073,0.002988696,0.0003028855,0.00009338178,0.001774169,0.001749415,0.9514588,0.04018518],"study_design_scores_gemma":[0.00003566627,0.0001315263,0.001134531,0.0004415649,0.00007811731,0.004025751,0.0003825225,0.0003295251,0.003181852,0.001037935,0.9891639,0.00005716684],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"dataset","genre_scores_codex":[0.002021746,0.007368589,0.00220663,0.1081032,0.8731512,0.00005974987,0.0008982448,0.0007902587,0.00540043],"genre_scores_gemma":[0.03649804,0.03479436,0.008710497,0.2371433,0.3482207,0.0002575887,0.004705689,0.003048177,0.3266217],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.9897172,"threshold_uncertainty_score":0.1700017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294704367104819,"score_gpt":0.2555006784312229,"score_spread":0.2425536347601747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}