{"id":"W4394266988","doi":"10.6084/m9.figshare.22618883","title":"Additional file 5 of Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Mechanism (biology); Pathological; Mechanism of action; Chemistry; Action (physics); Deconvolution; Biophysics; Computer science; Medicine; Biochemistry; Biology; Physics; Pathology; Algorithm; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001066239,0.001676262,0.001599507,0.001478952,0.0006720735,0.001780244,0.002265126,0.002090098,0.5351425],"category_scores_gemma":[0.006827162,0.0005577339,0.001567681,0.00210945,0.0003602614,0.001137358,0.0008898269,0.001663533,0.1056671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001417172,"about_ca_system_score_gemma":0.002024004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007911576,"about_ca_topic_score_gemma":0.01554946,"domain_scores_codex":[0.9995203,0.00006434072,0.00005769968,0.0001578547,0.0001183872,0.00008141781],"domain_scores_gemma":[0.9963722,0.002304314,0.0003027685,0.0003248641,0.0005047622,0.0001910524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004877319,0.0001272545,0.001760175,0.002896242,0.00009387654,0.00006176363,0.00001659054,0.00116815,0.0003333405,0.0007349509,0.9876808,0.004639099],"study_design_scores_gemma":[0.007308779,0.0004353081,0.01263826,0.001553437,0.0003952913,0.0005134214,0.0001114821,0.004136935,0.002612241,0.009591674,0.9605685,0.0001346815],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001169722,0.0000457909,0.0000747661,0.00004155253,0.00001046489,0.00001987417,0.9992568,0.0001226153,0.0003111065],"genre_scores_gemma":[0.00231676,0.0001079614,0.0008434115,0.0001995989,0.00002018146,0.0003176502,0.9943312,0.0001325878,0.00173071],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.5351425,"threshold_uncertainty_score":0.6630628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06615617381660906,"score_gpt":0.2928042814966063,"score_spread":0.2266481076799972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}