{"id":"W4394277913","doi":"10.6084/m9.figshare.20078618","title":"Sprouty-related proteins with EVH1 domain (SPRED2) prevents high-glucose induced endothelial–mesenchymal transition and endothelial injury by suppressing MAPK activation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Cell biology; Mesenchymal stem cell; MAPK/ERK pathway; Chemistry; Epithelial–mesenchymal transition; Transition (genetics); Biology; Biochemistry; Phosphorylation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001343695,0.000559235,0.0003867323,0.0001869151,0.000294881,0.000150018,0.0004722265,0.0007154437,0.05915904],"category_scores_gemma":[0.0002229147,0.000541107,0.0001045788,0.0002086042,0.0000408058,0.00003780549,0.0004255731,0.0009530059,0.00004970092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001128599,"about_ca_system_score_gemma":0.0003531609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000129557,"about_ca_topic_score_gemma":0.00002577865,"domain_scores_codex":[0.9969035,0.0004214216,0.0003929985,0.001010708,0.0006964571,0.000574893],"domain_scores_gemma":[0.9987376,0.00004141469,0.0003254802,0.000608061,0.0001007558,0.000186634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005180493,0.0001069731,0.000001161561,0.0003769884,0.0001073679,0.00001495614,0.00002960485,0.000002359528,0.4394888,1.246957e-7,0.5590825,0.0002711323],"study_design_scores_gemma":[0.001405798,0.001155938,0.0000477273,0.0008650281,0.00002832785,0.00002844645,0.00002331402,0.000003640024,0.5295715,0.000008996304,0.4663424,0.0005189041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.07975873,0.0001175778,0.000003701062,0.00004480917,0.0000575608,0.001818797,0.9181507,0.00003311946,0.00001496242],"genre_scores_gemma":[0.03722777,0.00002375138,0.00005111843,0.00006503313,0.0001928915,0.001218804,0.9609911,0.0001044167,0.0001250521],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.09274017,"threshold_uncertainty_score":0.9997041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087256345836097,"score_gpt":0.2497478290909234,"score_spread":0.2388752656325625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}