{"id":"W4394330649","doi":"10.6084/m9.figshare.20624170","title":"CCNE1 is a potential target of Metformin for tumor suppression of ovarian high-grade serous carcinoma","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bruyère; Centre for Advancing Health Outcomes; University of British Columbia","funders":"","keywords":"Metformin; Ovarian carcinoma; Serous fluid; Medicine; Oncology; Internal medicine; Cancer research; Ovarian cancer; Cancer; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005521966,0.0003082599,0.0004502328,0.00009022079,0.00008160534,0.00001086746,0.0005282314,0.0003057189,0.190577],"category_scores_gemma":[0.00009602316,0.0002983779,0.000383169,0.00008536297,0.00001532074,0.000003969384,0.0002454041,0.000186864,0.00001071548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001213314,"about_ca_system_score_gemma":0.0002209907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002099289,"about_ca_topic_score_gemma":0.00001744907,"domain_scores_codex":[0.9985356,0.00005636944,0.0004210471,0.0004441442,0.0002557871,0.0002870348],"domain_scores_gemma":[0.9988443,0.00002455566,0.0003023599,0.0006269505,0.0001145352,0.00008730477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002506302,0.000130593,0.00000162887,0.001071261,0.00009923382,0.00002683675,0.00001427515,0.00002571764,0.01757347,6.984205e-7,0.9807456,0.00006006828],"study_design_scores_gemma":[0.0008893037,0.0006470095,0.00003540483,0.000198824,0.00008941825,0.00003747528,0.00001525202,0.000009722887,0.1767343,0.00001225918,0.8210685,0.0002624927],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.00191554,0.001331244,0.00000767492,0.00002914451,0.0001782454,0.000556842,0.9959713,0.000004997186,0.000005007869],"genre_scores_gemma":[0.01236113,0.00002872548,0.0002128653,0.0001482334,0.00020104,0.0003252831,0.9865863,0.00004150228,0.00009494895],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.1905663,"threshold_uncertainty_score":0.9999468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527133075397399,"score_gpt":0.2450552820875139,"score_spread":0.2297839513335399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}