{"id":"W4394361914","doi":"10.6084/m9.figshare.22681095","title":"Additional file 2 of Toosendanin targeting eEF2 impedes Topoisomerase I & II protein translation to suppress esophageal squamous cell carcinoma growth","year":2023,"lang":"en","type":"dataset","venue":"Open MIND","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Esophageal squamous cell carcinoma; Translation (biology); Basal cell; Cancer research; Chemistry; Carcinoma; Internal medicine; Oncology; Biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001092422,0.001869258,0.001983312,0.001908414,0.0008417624,0.002365748,0.002371448,0.002380231,0.3915745],"category_scores_gemma":[0.008133448,0.0006500265,0.001845183,0.003359692,0.0004226986,0.001203066,0.001297711,0.001646132,0.1055257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001193792,"about_ca_system_score_gemma":0.00229378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009716396,"about_ca_topic_score_gemma":0.02172714,"domain_scores_codex":[0.9993225,0.00009832833,0.00008804635,0.0002627892,0.0001195884,0.0001086913],"domain_scores_gemma":[0.9963967,0.002246422,0.0002824167,0.0003626432,0.0004994808,0.0002122565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003938536,0.00008500953,0.002186049,0.005578755,0.0001747549,0.00006573771,0.00003962913,0.0006640645,0.0004023574,0.000503692,0.9865137,0.003392365],"study_design_scores_gemma":[0.005080291,0.0002209952,0.01566029,0.002685365,0.0005120292,0.0003161963,0.0001523578,0.001310585,0.001500093,0.004545848,0.9679027,0.0001134986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.00006096197,0.00002812434,0.00002635657,0.00002504813,0.000006919986,0.00000774356,0.9996463,0.00006481699,0.0001337019],"genre_scores_gemma":[0.0006650958,0.00005697816,0.0003034007,0.0001000645,0.000008493102,0.0001594857,0.9979898,0.00006866117,0.0006480221],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.3915745,"threshold_uncertainty_score":0.8678451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02576571234401226,"score_gpt":0.2704619636332117,"score_spread":0.2446962512891995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}