{"id":"W4394378590","doi":"10.6084/m9.figshare.19941580","title":"<i>Talaromyces marneffei</i> activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes","year":2022,"lang":"en","type":"dataset","venue":"TigerPrints (Clemson University)","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pyroptosis; AIM2; Caspase 1; Inflammasome; Cell biology; Chemistry; Biology; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002768334,0.0004667947,0.0003905577,0.000458402,0.0003442733,0.00005699665,0.001526279,0.0003865455,0.003149679],"category_scores_gemma":[0.0001098199,0.0004602595,0.0002362932,0.0006975062,0.0001386149,0.00001759806,0.00160292,0.000663829,0.0001620651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001490487,"about_ca_system_score_gemma":0.0002541645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001757941,"about_ca_topic_score_gemma":0.0007267824,"domain_scores_codex":[0.9977719,0.000287563,0.0002754572,0.0008080811,0.0002910664,0.00056599],"domain_scores_gemma":[0.9984134,0.00005844797,0.0001998823,0.001140622,0.00006593836,0.0001217229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004889126,0.0002176237,0.001124965,0.00006603698,0.0002354477,0.0001060325,0.0001326622,0.000105605,0.0234988,0.00001960335,0.9719222,0.00208217],"study_design_scores_gemma":[0.0005519541,0.0002246657,0.0008426772,0.00003807902,0.00005453692,0.000005447117,0.0008325749,0.000001392876,0.02155212,0.000005960013,0.9753392,0.0005513713],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.6465933,0.0002993011,0.00000630849,0.0005482835,0.0004245244,0.0009469488,0.3492374,0.00003304027,0.001910932],"genre_scores_gemma":[0.08686842,0.003548875,0.00004156991,0.001460754,0.0002156977,0.00006102861,0.9006271,0.0001100933,0.007066494],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.5597249,"threshold_uncertainty_score":0.9997849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007489652652552906,"score_gpt":0.207407150421202,"score_spread":0.1999174977686491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}