{"id":"W4394550349","doi":"10.6084/m9.figshare.22681092","title":"Additional file 1 of Toosendanin targeting eEF2 impedes Topoisomerase I & II protein translation to suppress esophageal squamous cell carcinoma growth","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Esophageal squamous cell carcinoma; Translation (biology); Basal cell; Cancer research; Chemistry; Carcinoma; Biology; Internal medicine; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009502563,0.001744675,0.002063583,0.001856237,0.0009384156,0.002497089,0.002399969,0.00251463,0.4207468],"category_scores_gemma":[0.008718931,0.0006648885,0.001777397,0.003662311,0.0003731348,0.001493626,0.00125985,0.001617889,0.1060448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001226458,"about_ca_system_score_gemma":0.00217798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00893125,"about_ca_topic_score_gemma":0.01863367,"domain_scores_codex":[0.9994138,0.00007439729,0.00007945938,0.0002357456,0.00009912503,0.00009744931],"domain_scores_gemma":[0.9962988,0.002392335,0.0003077808,0.0003444576,0.0004597358,0.0001968638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004935907,0.00008129657,0.002490651,0.006834879,0.0001780671,0.00006833972,0.0000394158,0.0005775713,0.0003863134,0.0005880136,0.9847184,0.003543439],"study_design_scores_gemma":[0.006425599,0.0002521125,0.01983817,0.003295428,0.0005724911,0.0003754785,0.0001666848,0.001394144,0.001557418,0.005721988,0.9602773,0.0001230779],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.00006086193,0.00003079583,0.00002277639,0.00002994305,0.000005785029,0.0000079169,0.9996461,0.00005769016,0.000138217],"genre_scores_gemma":[0.0009065723,0.00008467164,0.0003512177,0.0001335974,0.00001047082,0.0001952078,0.9974885,0.00007497772,0.0007547414],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.4207468,"threshold_uncertainty_score":0.8262343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02443596207852278,"score_gpt":0.243721531283457,"score_spread":0.2192855692049342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}