{"id":"W4394568226","doi":"10.1186/s12967-024-05113-x","title":"Melanocytes in regenerative medicine applications and disease modeling","year":2024,"lang":"en","type":"review","venue":"Journal of Translational Medicine","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Centre Hospitalier Universitaire de Québec; Canadian Institutes of Health Research; Mitacs; Fondation des pompiers du Québec pour les grands brûlés; Fondation des Maladies de l'Oeil; Université Laval","keywords":"Regenerative medicine; Melanocyte; Melanin; Disease; Medicine; Melanosome; Vitiligo; Integumentary system; Stem cell; Pathology; Neuroscience; Biology; Cell biology; Immunology; Cancer research; Melanoma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005189462,0.0006257195,0.00101636,0.00223476,0.0002540881,0.001136842,0.0006054689,0.001109517,0.004082984],"category_scores_gemma":[0.0005297988,0.0002241369,0.0004826873,0.001374711,0.0004142962,0.001096169,0.0007168418,0.001769011,0.0023725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000505158,"about_ca_system_score_gemma":0.0007425005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005945921,"about_ca_topic_score_gemma":0.001126106,"domain_scores_codex":[0.9998167,0.00003362753,0.00002545932,0.00003042462,0.00007480735,0.00001884579],"domain_scores_gemma":[0.9997621,0.0001171337,0.00002767151,0.000009513124,0.00005982138,0.00002378967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006607377,0.00007655049,0.0001557881,0.01555663,0.00007129875,0.0002870267,0.00006966492,0.0004024058,0.00649903,0.008869242,0.02390082,0.9440455],"study_design_scores_gemma":[0.000007842839,0.00005712084,0.000398771,0.002005203,0.00006078499,0.001148681,0.00003653736,0.00008430094,0.001213572,0.002007764,0.9929662,0.00001322729],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001738103,0.9968719,0.0003470565,0.000249526,0.0002394639,0.000007425419,0.00002589952,0.00001372381,0.002071321],"genre_scores_gemma":[0.001269242,0.9965317,0.0004318639,0.0002024566,0.0001582681,0.00001055254,0.00005162251,0.000003874222,0.001340414],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004082984,"threshold_uncertainty_score":0.01365894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05798967666630109,"score_gpt":0.3861669222777701,"score_spread":0.328177245611469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}