{"id":"W4394568524","doi":"10.3390/ijms25074070","title":"The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Care; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Novo Nordisk; Lawson Foundation","keywords":"Islet; Paracrine signalling; Internal medicine; Endocrinology; Biology; Enteroendocrine cell; Autocrine signalling; Pancreas; Endocrine system; Cell biology; Insulin; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003041197,0.0001618201,0.0002684196,0.0003933078,0.0002763531,0.0009559163,0.0002741696,0.000393277,0.001202357],"category_scores_gemma":[0.0004559381,0.0001253631,0.0001613465,0.0002097339,0.0005103024,0.000771848,0.0005683397,0.0008261375,0.0002682032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002531124,"about_ca_system_score_gemma":0.000219485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002567162,"about_ca_topic_score_gemma":0.0002748013,"domain_scores_codex":[0.9997662,0.00005719041,0.00001424777,0.00005846217,0.00004306366,0.00006081528],"domain_scores_gemma":[0.9997584,0.00004216674,0.00005541281,0.00003008347,0.00003172192,0.0000822672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00121656,0.000184137,0.02592712,0.0003182737,0.00004986484,0.001484803,0.001158038,0.0004309365,0.8577979,0.00395264,0.001223411,0.1062563],"study_design_scores_gemma":[0.00007986157,0.001191805,0.8047382,0.0002933034,0.0001267942,0.005842232,0.00356915,0.001419748,0.119687,0.01128577,0.05165963,0.0001065165],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9407571,0.04059509,0.004965615,0.0008905145,0.0003618358,0.00002721587,0.0002294218,0.0001076877,0.01206553],"genre_scores_gemma":[0.9900156,0.006368026,0.00127779,0.0001747328,0.0001851217,0.00002605791,0.00008709403,0.00002849453,0.001837124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001202357,"threshold_uncertainty_score":0.004022241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246025231041292,"score_gpt":0.2830102449424158,"score_spread":0.2705499926320029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}