{"id":"W4394579175","doi":"10.3389/frtra.2024.1336563","title":"Pretransplant, Th17 dominant alloreactivity in highly sensitized kidney transplant candidates","year":2024,"lang":"en","type":"article","venue":"Frontiers in Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University Health Centre; McGill University","keywords":"Kidney transplant; Immunology; Medicine; Renal transplant; Kidney transplantation; Kidney; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003062413,0.0003767629,0.0006232832,0.0008138393,0.00005118664,0.00005753023,0.00009095451,0.0002233623,0.00003990123],"category_scores_gemma":[0.000007617679,0.0003174323,0.0001953281,0.0006072518,0.00007312631,0.0003823739,0.000002128352,0.0004326242,0.00003002028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002373117,"about_ca_system_score_gemma":0.0002182772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007122169,"about_ca_topic_score_gemma":0.0004648815,"domain_scores_codex":[0.9977452,0.0001254009,0.0006138185,0.0006122662,0.0004071169,0.0004962152],"domain_scores_gemma":[0.9993821,0.0001124737,0.00004880988,0.0001998473,0.00002529827,0.0002314764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01485538,0.0009302454,0.8551269,0.01154291,0.0009201579,0.03409368,0.01596023,0.0002868694,0.05393801,0.0009477295,0.0006590619,0.01073883],"study_design_scores_gemma":[0.03095245,0.0007263696,0.7946949,0.02171246,0.002362844,0.003446281,0.0003904007,0.03257714,0.1081424,0.001188224,0.002289952,0.001516584],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9381713,0.001595053,0.05040707,0.00167412,0.002042444,0.001578282,0.001334038,0.0002368726,0.002960851],"genre_scores_gemma":[0.9863943,0.008094641,0.002867578,0.0002194075,0.00005843665,0.00008725273,0.001903652,0.00005153289,0.0003231537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.060432,"threshold_uncertainty_score":0.9999278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008565113645135637,"score_gpt":0.258668345121605,"score_spread":0.2501032314764693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}