{"id":"W4394579175","doi":"10.3389/frtra.2024.1336563","title":"Pretransplant, Th17 dominant alloreactivity in highly sensitized kidney transplant candidates","year":2024,"lang":"en","type":"article","venue":"Frontiers in Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University Health Centre; McGill University","keywords":"Kidney transplant; Immunology; Medicine; Renal transplant; Kidney transplantation; Kidney; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002314884,0.000178275,0.0002124042,0.0003972886,0.0003146683,0.0004106539,0.0001065645,0.0002251277,0.00348967],"category_scores_gemma":[0.0003510595,0.00008995968,0.0001676619,0.000241818,0.0001592556,0.0001667234,0.0001957904,0.0003196452,0.0003005719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001264108,"about_ca_system_score_gemma":0.0002065266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001761697,"about_ca_topic_score_gemma":0.0002409016,"domain_scores_codex":[0.9998701,0.00002903866,0.00001367127,0.00003442452,0.00002074672,0.00003203392],"domain_scores_gemma":[0.9997852,0.00004029866,0.00008491922,0.00001452939,0.00001574896,0.00005921548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001843886,0.0005079371,0.8384174,0.0003110674,0.00007602163,0.006630895,0.0004964448,0.0002923337,0.1210953,0.0002735822,0.0004529299,0.02960218],"study_design_scores_gemma":[0.0000451158,0.003028556,0.9556857,0.00005119144,0.0001148055,0.02320777,0.0005874198,0.0004900426,0.01235674,0.0003130161,0.004106967,0.00001271476],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998184,0.0006958572,0.0001945738,0.00003319807,0.00000927345,0.00001411713,0.00005510771,0.00000883876,0.0008049283],"genre_scores_gemma":[0.9992471,0.0001674968,0.0001426614,0.00003182043,0.000021146,0.000008824662,0.00006284142,0.000002208727,0.0003158725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00348967,"threshold_uncertainty_score":0.01167411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008565113645135637,"score_gpt":0.258668345121605,"score_spread":0.2501032314764693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}