{"id":"W4394598866","doi":"10.1212/wnl.0000000000204975","title":"Epigenetic Age and Brain Health Events: Findings from the Health and Retirement Study (P2-9.004)","year":2024,"lang":"en","type":"article","venue":"Neurology","topic":"Diet and metabolism studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Epigenetics; Health and Retirement Study; Neuroscience; Psychology; Gerontology; Medicine; Physical medicine and rehabilitation; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009089196,0.0002191199,0.0002181322,0.0005271226,0.000536308,0.0005153146,0.0003944833,0.0005968417,0.005742615],"category_scores_gemma":[0.002411419,0.0001480775,0.0004396889,0.0007355981,0.0002967329,0.0004784534,0.0005888029,0.0006357554,0.000339651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001671313,"about_ca_system_score_gemma":0.0003886312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01256272,"about_ca_topic_score_gemma":0.01727907,"domain_scores_codex":[0.9997888,0.00006351274,0.00001541198,0.00004773094,0.0000246778,0.00005993005],"domain_scores_gemma":[0.9989032,0.0002010891,0.0004172146,0.00008880463,0.000107251,0.0002824424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000471793,0.0001269276,0.9929898,0.00002574817,0.0001977885,0.0001723348,0.0003341023,0.00003573719,0.0007601823,0.0002437161,0.0004789845,0.004163027],"study_design_scores_gemma":[0.00001118864,0.00007155998,0.9991371,0.00000519624,0.00005486218,0.00004433618,0.0001674525,0.00002166976,0.00006512808,0.0001224634,0.0002975224,0.000001526589],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960656,0.0004568298,0.0001356201,0.0007327714,0.00002653378,0.000007325872,0.0006951343,0.000002560376,0.001877776],"genre_scores_gemma":[0.9984215,0.0001268434,0.00007196539,0.0001728904,0.00003489806,0.000006961604,0.0002971723,0.000001536725,0.0008662258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01256272,"threshold_uncertainty_score":0.02497917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03451800121741262,"score_gpt":0.3340724384328791,"score_spread":0.2995544372154665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}