{"id":"W4394599957","doi":"10.1212/wnl.0000000000205102","title":"Safety, Tolerability, and Clinical Assessment of Bemdaneprocel for Parkinson’s Disease: 18-month Results from a Phase 1 Study (P9-3.007)","year":2024,"lang":"en","type":"article","venue":"Neurology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Western Hospital","funders":"","keywords":"Tolerability; Medicine; Parkinson's disease; Disease; Psychology; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002427257,0.0009978019,0.001133727,0.0003595169,0.0005233423,0.000584069,0.0005454011,0.001139056,0.002857698],"category_scores_gemma":[0.001647178,0.0003148021,0.0008963362,0.0002711334,0.0005570472,0.0007523707,0.0002245895,0.002463263,0.000729715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004410422,"about_ca_system_score_gemma":0.0009310423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007269537,"about_ca_topic_score_gemma":0.001834867,"domain_scores_codex":[0.9994627,0.0002518922,0.00002930665,0.00007303213,0.00009967934,0.00008344007],"domain_scores_gemma":[0.9983256,0.000305032,0.0005810156,0.00010042,0.0002132417,0.0004745869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.649302,0.08333283,0.02137051,0.001245794,0.002213901,0.0004295999,0.0005134327,0.001544439,0.07210008,0.0001741716,0.007801832,0.1599714],"study_design_scores_gemma":[0.2213927,0.6591934,0.1024752,0.00007732753,0.000876491,0.0006874974,0.0001166515,0.0008432597,0.009691325,0.0002313363,0.004344533,0.00007035288],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914582,0.001765576,0.0008455855,0.0002447675,0.00005406393,0.001564689,0.002075348,0.0001045331,0.001887223],"genre_scores_gemma":[0.9865212,0.001603301,0.00211447,0.0008126289,0.0001815622,0.001847828,0.004284858,0.00005410703,0.002580004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002857698,"threshold_uncertainty_score":0.01283669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0531110393348037,"score_gpt":0.4063640330352908,"score_spread":0.3532529937004871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}