{"id":"W4394621232","doi":"10.1016/j.tem.2024.03.005","title":"Is MASLD lost in translation in mice?","year":2024,"lang":"en","type":"article","venue":"Trends in Endocrinology and Metabolism","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Translation (biology); Context (archaeology); Disease; Human disease; Drug development; Stressor; Medicine; Liver disease; Biology; Drug; Neuroscience; Internal medicine; Pharmacology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005222187,0.0001249727,0.0002811713,0.0007468686,0.000009413408,0.000007932214,0.00002964677,0.00007336349,0.0003854722],"category_scores_gemma":[0.000006056841,0.0001047891,0.00005405265,0.0003701354,0.00004979357,0.00007876457,0.00001327197,0.0002005909,0.00003606153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003105305,"about_ca_system_score_gemma":0.00002504072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002673148,"about_ca_topic_score_gemma":0.0004977008,"domain_scores_codex":[0.999122,0.00004447853,0.0002105853,0.0002949669,0.00006649226,0.0002615409],"domain_scores_gemma":[0.9997657,0.00006862351,0.00001160771,0.00009703441,0.000005625418,0.00005143681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0002020793,0.0007030996,0.3245959,0.0001111759,0.000122757,0.002517338,0.003937928,0.000004241093,0.0003380945,0.01198016,0.0004803995,0.6550068],"study_design_scores_gemma":[0.003336203,0.00003896571,0.9717011,0.0001107216,0.0001356795,0.00005710332,0.0001099336,0.0001628026,0.001061567,0.0008934811,0.02229619,0.00009620334],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9262371,0.06119951,0.000001216159,0.005411567,0.0002251289,0.0001224006,0.00002329012,0.00002276162,0.006756994],"genre_scores_gemma":[0.9933916,0.00543182,0.0001054864,0.0003425693,0.00005339766,0.00005310071,0.00003208161,0.00001009412,0.0005799039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6549106,"threshold_uncertainty_score":0.4273177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03392336940108237,"score_gpt":0.3234414168628409,"score_spread":0.2895180474617585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}