{"id":"W4394621364","doi":"10.1002/prot.26689","title":"Adhesin domains responsible for binding bacteria to surfaces they colonize project outwards from companion split domains","year":2024,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Queen's University","keywords":"Bacterial adhesin; Ligand (biochemistry); Plasma protein binding; Biology; Biophysics; Chemistry; Cell biology; Escherichia coli; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000707804,0.0003772315,0.0002861785,0.0002288093,0.0002792623,0.0005320637,0.0002479666,0.0003115429,0.002572869],"category_scores_gemma":[0.0001933763,0.0002369005,0.0005041608,0.0003493633,0.0001746959,0.0003413305,0.0003670297,0.0003844157,0.0009854593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000203881,"about_ca_system_score_gemma":0.0003891473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009912244,"about_ca_topic_score_gemma":0.001103949,"domain_scores_codex":[0.9999537,0.000002948721,0.000002620112,0.00001221193,0.00001980685,0.000008722818],"domain_scores_gemma":[0.9999298,0.00001036342,0.00001909808,0.0000102709,0.00001409353,0.00001637812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005120482,0.0001328055,0.03288938,0.000481301,0.0001206368,0.001123516,0.0004152249,0.01378526,0.8666614,0.008728207,0.00259568,0.0725545],"study_design_scores_gemma":[0.0002063145,0.0007565015,0.2433212,0.0001521722,0.0002654497,0.007936367,0.000973401,0.1862275,0.4884591,0.01109969,0.06050618,0.00009606608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9496433,0.001315836,0.04005501,0.0001372828,0.00005450419,0.00004489965,0.001241071,0.001132467,0.006375612],"genre_scores_gemma":[0.9584345,0.0007629017,0.03263108,0.00006245258,0.000008143972,0.00002503064,0.003248558,0.00009449205,0.004732842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002572869,"threshold_uncertainty_score":0.00860709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187383403901384,"score_gpt":0.2485011912270067,"score_spread":0.2366273571879928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}