{"id":"W4394621364","doi":"10.1002/prot.26689","title":"Adhesin domains responsible for binding bacteria to surfaces they colonize project outwards from companion split domains","year":2024,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Queen's University","keywords":"Bacterial adhesin; Ligand (biochemistry); Plasma protein binding; Biology; Biophysics; Chemistry; Cell biology; Escherichia coli; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001260439,0.0002520726,0.0002018492,0.0001026365,0.0001896858,0.0002652387,0.0001106691,0.0002701574,0.00002740705],"category_scores_gemma":[0.00008059563,0.0001871815,0.00007806665,0.0001666467,0.00004475464,0.00003441256,0.00009497649,0.0001212822,0.000006156438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003389736,"about_ca_system_score_gemma":0.0001006548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000279175,"about_ca_topic_score_gemma":0.00005367473,"domain_scores_codex":[0.9989007,0.0000338636,0.0003391103,0.0003156785,0.0001543458,0.0002563179],"domain_scores_gemma":[0.9994981,0.00002577593,0.00008952608,0.0001977713,0.00008666522,0.0001022208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006473534,0.000007218991,0.0002335605,0.0002422911,0.00007202642,3.451257e-7,0.0003285091,0.000004960328,0.9913592,0.0003684244,0.0006871391,0.006049004],"study_design_scores_gemma":[0.001476346,0.001413886,0.01173595,0.0002448258,0.0001436097,0.00003581275,0.0004920958,0.004658817,0.8498585,0.002668495,0.1264049,0.0008666706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982626,0.0001362765,0.01351678,0.0003773924,0.0006203929,0.001195404,0.001391888,0.00007647119,0.00005940358],"genre_scores_gemma":[0.9548331,0.00004158058,0.0415628,0.0002787625,0.0004135564,0.00005894011,0.002519512,0.00002667459,0.0002650078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1415006,"threshold_uncertainty_score":0.7633039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187383403901384,"score_gpt":0.2485011912270067,"score_spread":0.2366273571879928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}