{"id":"W4394683596","doi":"10.3390/cells13080664","title":"Focal Adhesion’s Role in Cardiomyocytes Function: From Cardiomyogenesis to Mechanotransduction","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Mechanotransduction; Focal adhesion; Cell biology; Paxillin; Integrin; Vinculin; Extracellular matrix; Cell adhesion; Crosstalk; Signal transduction; PI3K/AKT/mTOR pathway; Biology; Chemistry; Adhesion; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015433,0.0004149377,0.0008009602,0.0002374004,0.0000491756,0.00006816549,0.0002318023,0.0005076724,0.0001248335],"category_scores_gemma":[0.00001304084,0.0003795486,0.0008523783,0.000325403,0.0000106665,0.00000411381,0.0001588272,0.0002658619,0.0006709337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001057201,"about_ca_system_score_gemma":0.0001638061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001400347,"about_ca_topic_score_gemma":0.00005841324,"domain_scores_codex":[0.998147,0.0001162528,0.0004442974,0.0008514239,0.0001659511,0.0002750504],"domain_scores_gemma":[0.99914,0.00001501354,0.00007193993,0.0005941211,0.00005022122,0.000128678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004086318,0.00007241686,3.444549e-7,0.001607653,0.0008394193,0.00003307125,0.00004232124,0.00004793776,0.1385621,0.00007673755,0.0145856,0.8440915],"study_design_scores_gemma":[0.00006968893,0.0001232888,2.706139e-7,0.001041344,0.0009558828,0.00001425051,0.00003777657,0.00001134965,0.02218657,0.00006692595,0.975112,0.0003807042],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001407402,0.9933667,0.001838138,0.00001922764,0.003302136,0.000535855,0.0002460387,0.00002720792,0.0005239912],"genre_scores_gemma":[0.0005873219,0.9942282,0.000158676,0.00005477993,0.001511563,0.0002646254,0.0009460133,0.0001027654,0.002146018],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9605263,"threshold_uncertainty_score":0.9998657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905320796356345,"score_gpt":0.2814093667501413,"score_spread":0.2623561587865778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}