{"id":"W4394691262","doi":"10.20944/preprints202404.0567.v1","title":"Immunogenicity of Non-mutated Ovarian Cancer-Specific Antigens","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Ovarian Cancer Canada","keywords":"Immunogenicity; Antigen; Biology; Immunotherapy; CD8; Cytotoxic T cell; Molecular biology; Cancer research; Allotype; Ovarian cancer; Epitope; Cancer immunotherapy; Cancer; Computational biology; Immunology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272058,0.0001855331,0.0001497056,0.0001501997,0.00007776351,0.0002219744,0.0000929377,0.000167229,0.001243797],"category_scores_gemma":[0.0002384867,0.00006143211,0.0001489146,0.00009478781,0.0001004271,0.0001104668,0.0002017659,0.0002579039,0.000263609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001090044,"about_ca_system_score_gemma":0.00006649961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009333301,"about_ca_topic_score_gemma":0.00007076784,"domain_scores_codex":[0.9998797,0.00002050989,0.000009396775,0.00002149575,0.00003349796,0.00003540932],"domain_scores_gemma":[0.9998957,0.00002838457,0.00002390035,0.00001720465,0.00001415026,0.00002055325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007803492,0.00001227603,0.001598973,0.00001666431,0.000004140755,0.00003531026,0.000009528511,0.00004960931,0.9970632,0.00002368772,0.00001510432,0.001093413],"study_design_scores_gemma":[0.00001894379,0.0008340448,0.06158214,0.000007502821,0.0000330263,0.001506209,0.00006640355,0.001758435,0.9319128,0.0001536073,0.002122523,0.000004323078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990621,0.0001896349,0.0003435233,0.00001088577,0.000004408589,0.000004551149,0.00006960901,0.000005997122,0.0003092437],"genre_scores_gemma":[0.9987413,0.0001536577,0.0003565609,0.00001651464,0.000008131668,0.000005928232,0.0003025983,0.000007325697,0.0004080376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001243797,"threshold_uncertainty_score":0.004160941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06850715705578556,"score_gpt":0.3344977010613667,"score_spread":0.2659905440055812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}