{"id":"W4394691787","doi":"10.3390/vaccines12040404","title":"Mucosal Vaccination with a Newcastle Disease Virus-Vectored Vaccine Reduces Viral Loads in SARS-CoV-2-Infected Cynomolgus Macaques","year":2024,"lang":"en","type":"article","venue":"Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Health Sciences Centre; Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Vaccination; Medicine; Virology; Immunology; Immunization; Immune system; Virus; Disease; Outbreak; Pandemic; Vaccine efficacy; Viral load; Clinical trial; Viral shedding; Infectious disease (medical specialty); Coronavirus disease 2019 (COVID-19); Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002895989,0.0004877559,0.0005886112,0.001096656,0.00009722299,0.000224791,0.0002639747,0.0001720362,0.00009424072],"category_scores_gemma":[0.0002902979,0.0003670277,0.0001759932,0.001711906,0.00002374852,0.0005341476,0.0001244211,0.0005288981,0.0002207997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003155007,"about_ca_system_score_gemma":0.0006508332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001198906,"about_ca_topic_score_gemma":0.001353405,"domain_scores_codex":[0.9971293,0.0001254522,0.0005432517,0.0008805749,0.0006081361,0.0007133036],"domain_scores_gemma":[0.9988227,0.0001794029,0.00008049064,0.0005409284,0.0002609906,0.0001155108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008005635,0.000892416,0.1600294,0.001087015,0.0003261559,0.003370983,0.000680066,0.000004723975,0.7892814,0.0003075329,0.008296574,0.02771812],"study_design_scores_gemma":[0.005710471,0.00112613,0.3389328,0.0007630741,0.000291472,0.0002030572,0.00008853978,0.00629097,0.6165134,0.0005688905,0.02881548,0.0006957519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910843,0.003662927,0.0001123136,0.002032954,0.0003410619,0.000996543,0.00003500992,0.0005998785,0.001134963],"genre_scores_gemma":[0.9946683,0.0000551035,0.0001459402,0.003857983,0.0007319796,0.0002001348,0.00005928853,0.0001189757,0.0001622896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1789034,"threshold_uncertainty_score":0.9998782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02993395179787141,"score_gpt":0.3473430758248404,"score_spread":0.317409124026969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}