{"id":"W4394720683","doi":"10.1152/japplphysiol.00031.2024","title":"Cerebrovascular dysfunction and depressive symptoms in preclinical models: insights from a scoping review","year":2024,"lang":"en","type":"review","venue":"Journal of Applied Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Institute of Health Services and Policy Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Medicine; Depression (economics); CLARITY; Depressive symptoms; Serotonergic; MEDLINE; Executive dysfunction; Psychology; Bioinformatics; Clinical psychology; Neuroscience; Psychiatry; Internal medicine; Cognition; Biology; Serotonin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00488072,0.001067938,0.003076149,0.008822034,0.0005331155,0.002900818,0.001131028,0.001564124,0.003453173],"category_scores_gemma":[0.01484181,0.0005859539,0.002545821,0.007338859,0.0006209607,0.001921438,0.001498691,0.00148803,0.0006461057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001680771,"about_ca_system_score_gemma":0.007308947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003529021,"about_ca_topic_score_gemma":0.009787281,"domain_scores_codex":[0.9984848,0.0004088511,0.0005335237,0.0001416202,0.0003665114,0.0000647799],"domain_scores_gemma":[0.9881278,0.009254791,0.00108869,0.000219988,0.001192548,0.0001162774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001425519,0.00004773166,0.0004727305,0.4353973,0.001267104,0.0002922029,0.0005175566,0.0003178785,0.0008393502,0.003002124,0.009620972,0.5480825],"study_design_scores_gemma":[0.00003560113,0.0001504377,0.002361763,0.7667445,0.005834316,0.0008626853,0.0005231022,0.0001624807,0.0004201979,0.003024807,0.2198326,0.00004755913],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000205522,0.9987118,0.0001651453,0.0002818878,0.0001185047,0.00004920331,0.00007838514,0.000004631271,0.0003849354],"genre_scores_gemma":[0.001031742,0.9982657,0.0002855267,0.0001532009,0.00004840933,0.00005298705,0.00006142808,0.000001626883,0.00009948783],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008822034,"threshold_uncertainty_score":0.02581203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07338309376411682,"score_gpt":0.3510816471804292,"score_spread":0.2776985534163124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}