{"id":"W4394722624","doi":"10.1016/j.healun.2024.02.1200","title":"CRISPR Genome Engineering in Donor Lung During Cyclic EVLP with 10°C Preservation: Usage of TorEx Lung Perfusion System","year":2024,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"CRISPR; Lung; Genome engineering; Medicine; Biology; Cardiology; Internal medicine; Genome editing; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002341311,0.000273669,0.0002975307,0.0001469626,0.0002547665,0.0004193427,0.0003261654,0.0004206961,0.002013867],"category_scores_gemma":[0.000168303,0.0001525181,0.0002888316,0.000106657,0.0003540622,0.0001998724,0.0003188365,0.0006678642,0.000344575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994793,"about_ca_system_score_gemma":0.0003224617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007233612,"about_ca_topic_score_gemma":0.001333966,"domain_scores_codex":[0.9997161,0.00002530922,0.00002027539,0.0001105983,0.00005939332,0.00006840577],"domain_scores_gemma":[0.9998926,0.00002560253,0.00002889092,0.00002104942,0.00001080625,0.00002107988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006603597,0.0000243133,0.0001503494,0.00004611861,0.000004825463,0.00005369501,0.00003039485,0.00008818843,0.9974722,0.0001772707,0.0000749695,0.001811516],"study_design_scores_gemma":[0.000009231794,0.0001559185,0.001821629,0.000006603677,0.00001745779,0.0001856777,0.00002827592,0.0006828906,0.9939277,0.00004755147,0.003106167,0.00001078213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961805,0.001024707,0.03037632,0.0001507428,0.0001833171,0.0001692256,0.000786768,0.0006953836,0.004808472],"genre_scores_gemma":[0.9816234,0.0003910506,0.01213849,0.0001241307,0.00001239416,0.000174479,0.0007319952,0.0001211251,0.004682797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002013867,"threshold_uncertainty_score":0.006737053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009521409063424321,"score_gpt":0.2716795364601987,"score_spread":0.2621581273967744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}