{"id":"W4394723192","doi":"10.1016/j.healun.2024.02.1092","title":"The ABCs of DSAs: Incidence, Class, Gene and Strength of Donor Specific Antibody Development in the First Year After Heart Transplant","year":2024,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Donor specific antibodies; Antibody; Incidence (geometry); Heart transplantation; Medicine; Gene; Immunology; Biology; Genetics; Internal medicine; Transplantation; Human leukocyte antigen; Mathematics; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001267184,0.0002617652,0.000461187,0.001515624,0.0003393707,0.001187646,0.0005090624,0.0006947384,0.003398781],"category_scores_gemma":[0.004781567,0.0002151237,0.0006026275,0.001355744,0.000391888,0.001136803,0.0007067406,0.001166538,0.0004449272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003969631,"about_ca_system_score_gemma":0.0004452681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002756451,"about_ca_topic_score_gemma":0.002463669,"domain_scores_codex":[0.9992419,0.0001802372,0.00009892933,0.0001018956,0.0001688638,0.0002080635],"domain_scores_gemma":[0.9950682,0.00102822,0.00242056,0.0002209721,0.0004035887,0.0008584869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001909139,0.00001962419,0.9985365,0.000004831589,0.00002608211,0.00004947537,0.00002101362,0.00002182509,0.0000725123,0.00002241913,0.00004487324,0.0009899717],"study_design_scores_gemma":[0.000004470704,0.0001978335,0.9985383,0.000007890409,0.00003230988,0.0006226171,0.0001473589,0.0001418531,0.00007621526,0.00004990198,0.0001754549,0.000005835871],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976422,0.0005540847,0.00009347558,0.00005141282,0.00001183762,0.000007226275,0.0004067808,0.000005942799,0.001227005],"genre_scores_gemma":[0.9992182,0.0001191022,0.00005380839,0.0000142375,0.00001646079,0.000003766311,0.0003039092,0.000001643968,0.0002688876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003398781,"threshold_uncertainty_score":0.01137006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296438945449425,"score_gpt":0.2981433297761946,"score_spread":0.2851789403217004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}