{"id":"W4394727953","doi":"10.1126/science.ado0431","title":"Human telomere length is chromosome end–specific and conserved across individuals","year":2024,"lang":"en","type":"article","venue":"Science","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Strong; Johns Hopkins University; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Telomere; Biology; Chromosome; Genetics; Telomerase; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002787181,0.0001558899,0.0002248559,0.0005028517,0.0002455509,0.0004213063,0.0001750106,0.0003015573,0.001233597],"category_scores_gemma":[0.0005817417,0.0001368705,0.0001938602,0.000619898,0.0001918477,0.0002647051,0.0003001762,0.0003350599,0.0005896757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153178,"about_ca_system_score_gemma":0.0001608003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007143119,"about_ca_topic_score_gemma":0.00131184,"domain_scores_codex":[0.9997767,0.00001896872,0.00001364636,0.0001048015,0.00006518899,0.00002080285],"domain_scores_gemma":[0.9996884,0.00006636573,0.0001201936,0.00004304282,0.00005524447,0.00002668169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001690847,0.00001158813,0.01301774,0.00009479917,0.00003839244,0.00006089714,0.0001115464,0.0002066416,0.9541696,0.000419432,0.0003241048,0.03137602],"study_design_scores_gemma":[0.00001678426,0.0006695826,0.3107149,0.00006200214,0.0001178268,0.001671666,0.000185116,0.002646487,0.6564947,0.001858587,0.02549668,0.00006565171],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9367985,0.01021476,0.03942823,0.0003780377,0.0001063545,0.00003749965,0.00629947,0.0004675285,0.006269631],"genre_scores_gemma":[0.9768944,0.002656986,0.0149435,0.0002250102,0.00003308683,0.00004817978,0.002269643,0.0000460536,0.002883059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001233597,"threshold_uncertainty_score":0.004126847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03608511468908457,"score_gpt":0.342048200174167,"score_spread":0.3059630854850824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}