{"id":"W4394728296","doi":"10.21203/rs.3.rs-4014898/v1","title":"Unveiling the Brazilian Kefir Microbiome: Discovery of a novel Lactobacillus kefiranofaciens (LkefirU) genome and in silico prospection of bioactive peptides with potential anti-Alzheimer properties","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Universidade Federal de Uberlândia; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"In silico; Prospection; Microbiome; Gut microbiome; Genome; Biology; Computational biology; Geography; Bioinformatics; Genetics; Gene; Archaeology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003612558,0.0007489228,0.0006871386,0.0005686426,0.0003762091,0.001024744,0.0002279576,0.0006760557,0.0007255666],"category_scores_gemma":[0.0007735666,0.0002222262,0.0008185761,0.0006716151,0.0002256716,0.0004894189,0.0005482918,0.0005427271,0.0002310815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003768363,"about_ca_system_score_gemma":0.000735936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00625385,"about_ca_topic_score_gemma":0.008502064,"domain_scores_codex":[0.9998633,0.00002725919,0.000006956706,0.00003833373,0.0000284377,0.00003572831],"domain_scores_gemma":[0.9998702,0.00003630729,0.00002824898,0.00001644888,0.00002307317,0.00002568655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004889946,0.00004643909,0.005943084,0.0003574948,0.0000897194,0.0002288021,0.0002220784,0.001317378,0.9748374,0.0002462539,0.0002293518,0.01599299],"study_design_scores_gemma":[0.0001936414,0.001336721,0.2015465,0.0004613706,0.001513458,0.002533527,0.003791606,0.03739067,0.6980885,0.002716882,0.05026431,0.000162811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850878,0.005277254,0.005573113,0.0008455032,0.00004125218,0.00002334118,0.001848071,0.0001072301,0.001196418],"genre_scores_gemma":[0.9818045,0.003274211,0.01164117,0.0001265657,0.00001694835,0.0000149725,0.002381163,0.00005577021,0.0006846247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00625385,"threshold_uncertainty_score":0.0124349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05472074924851878,"score_gpt":0.2918016313252297,"score_spread":0.237080882076711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}