{"id":"W4394758473","doi":"10.1111/imm.13777","title":"Prevention and treatment of HPV‐related cancer through a mRNA vaccine expressing APC‐targeting antigen","year":2024,"lang":"en","type":"article","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada)","funders":"National Natural Science Foundation of China","keywords":"Antigen; Immune system; CD8; Biology; Messenger RNA; Cancer research; Immunology; Cancer vaccine; Immunotherapy; Virology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006996705,0.000185972,0.0001719659,0.0001089397,0.00005758857,0.0001334838,0.00009589333,0.0002144086,0.0008976703],"category_scores_gemma":[0.00006870984,0.00004815446,0.0001583643,0.00006282236,0.0001272161,0.0001463015,0.0001314111,0.0003280815,0.000205456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009619428,"about_ca_system_score_gemma":0.0001216759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001199925,"about_ca_topic_score_gemma":0.0001092221,"domain_scores_codex":[0.9999546,0.000007860548,0.000003239299,0.000008898695,0.00001329642,0.00001211085],"domain_scores_gemma":[0.9999756,0.000004524061,0.000006722676,0.00000296053,0.000005287842,0.000004995001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008483083,0.00006643498,0.0001455113,0.00007635981,0.000003914873,0.00003680421,0.000006365165,0.0001921348,0.9927288,0.000156116,0.00005442195,0.006448287],"study_design_scores_gemma":[0.00003079818,0.001879966,0.001053901,0.00001070392,0.00002716118,0.0003333191,0.00001288917,0.00116824,0.9902497,0.00009658981,0.005132895,0.000003815974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828445,0.004828368,0.009995865,0.0001857023,0.0001332336,0.00006806126,0.0001042696,0.00009668337,0.00174341],"genre_scores_gemma":[0.9914823,0.00204973,0.004176609,0.00005719311,0.00003226351,0.00003386893,0.0001284627,0.00001024368,0.002029413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008976703,"threshold_uncertainty_score":0.003003001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553902647916961,"score_gpt":0.291910998784511,"score_spread":0.2763719723053414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}