{"id":"W4394769654","doi":"10.1126/sciadv.adg7894","title":"Smaug regulates germ plasm assembly and primordial germ cell number in Drosophila embryos","year":2024,"lang":"en","type":"article","venue":"Science Advances","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Germ plasm; Germ line development; Biology; Germ cell; Cell biology; oskar; Embryo; Translation (biology); Messenger RNA; Oocyte; RNA-binding protein; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003151287,0.0001097037,0.00008600332,0.00006302615,0.0001091852,0.00005690301,0.0001421724,0.00008190887,0.000007218767],"category_scores_gemma":[0.00003006064,0.00009311738,0.00002359584,0.0002649307,0.0004351363,0.00003961692,0.000102366,0.00006095005,0.00002109846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001752048,"about_ca_system_score_gemma":0.0001498193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003812891,"about_ca_topic_score_gemma":0.00003817202,"domain_scores_codex":[0.9990229,0.00001975407,0.000136112,0.0004654707,0.0001166749,0.0002391146],"domain_scores_gemma":[0.9997556,0.00001590212,0.00003273512,0.0001183125,0.00002351183,0.00005397941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001514168,0.00001403825,0.01974679,0.00002465347,0.000002964301,0.000004521401,0.0000617586,0.00005047063,0.9651601,0.000124036,0.00006643109,0.01472907],"study_design_scores_gemma":[0.0001527868,0.00005789611,0.08623618,0.00002088577,0.000003061369,0.00003073268,0.00004887539,0.00008759867,0.8983935,0.00117187,0.01361771,0.0001789539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941581,0.002035405,0.00003237019,0.0001483629,0.0004099767,0.000121033,0.000004084072,0.00001510928,0.003075531],"genre_scores_gemma":[0.9978329,0.0001864798,0.0006908065,0.00007208671,0.00009033729,0.0000138818,0.00001840431,0.000006291856,0.001088791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06676668,"threshold_uncertainty_score":0.3797217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004719954938736996,"score_gpt":0.2623340802616664,"score_spread":0.2576141253229294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}