{"id":"W4394823988","doi":"10.1097/ju9.0000000000000137","title":"Expert Perspectives on Controversies in Castration-Sensitive Prostate Cancer Management: Narrative Review and Report of the First US Prostate Cancer Conference Part 1","year":2024,"lang":"en","type":"article","venue":"JU Open Plus","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Janssen Biotech; Foundation Medicine; National Cancer Institute; Cancer Center, University of Colorado; National Institutes of Health; Astellas Pharma; Daiichi-Sankyo; Invitae; National Center for Advancing Translational Sciences; Seagen; UroGen Pharma; Clovis Oncology; Sanofi; Exelixis; Advanced Accelerator Applications; Regeneron Pharmaceuticals; Prostate Cancer Foundation; Bristol-Myers Squibb; AstraZeneca; Myriad Genetics; Celgene; Amgen; Pfizer","keywords":"Prostate cancer; Cancer; Prostate; Narrative; Narrative review; Medicine; Management of prostate cancer; Castration; Gynecology; Internal medicine; Intensive care medicine; Art; Hormone; Literature","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002348749,0.0001737168,0.0004198179,0.00006483838,0.0001155796,0.00008734447,0.0001042644,0.00003372132,0.0001259512],"category_scores_gemma":[0.00004760114,0.0001035312,0.00005026248,0.0003062028,0.0002478412,0.0001724162,0.0001406292,0.0001951111,0.000002926257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004808656,"about_ca_system_score_gemma":0.0005770621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002928958,"about_ca_topic_score_gemma":0.002187845,"domain_scores_codex":[0.9987236,0.00005903983,0.0002763011,0.0004454722,0.0002715884,0.0002240451],"domain_scores_gemma":[0.9993193,0.00006794369,0.0001027482,0.0002368312,0.0002140936,0.00005912646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"qualitative","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01121775,0.0009634325,0.0442944,0.02075272,0.005698298,0.0134858,0.6429393,0.0001790264,0.001569611,0.009125708,0.2167555,0.03301841],"study_design_scores_gemma":[0.02362565,0.002527303,0.1510714,0.1323303,0.002000395,0.0005720567,0.2168987,0.0009402129,0.01585802,0.0004355529,0.4521373,0.001603109],"study_design_candidate":"qualitative","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5131127,0.2539495,0.000001332901,0.1667201,0.0006719893,0.0182675,0.0005527649,0.00005001627,0.04667412],"genre_scores_gemma":[0.8310636,0.1398674,0.00002003976,0.000956543,0.00004543293,0.001317522,0.00002089765,0.0000180122,0.02669055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4260406,"threshold_uncertainty_score":0.4427728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03931946968918519,"score_gpt":0.3789558317343568,"score_spread":0.3396363620451716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}