{"id":"W4394917897","doi":"10.1182/blood.2023023755","title":"HOXA9 and β-catenin safeguard HSC integrity","year":2024,"lang":"en","type":"letter","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"Medical Research Council","keywords":"Safeguard; Political science; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001278181,0.0004787358,0.0007594943,0.0003684033,0.001753529,0.002280253,0.0006650219,0.01966349,0.003836866],"category_scores_gemma":[0.00612163,0.0003680685,0.0005763763,0.0002366465,0.002257016,0.00119302,0.0006828663,0.01694046,0.002712828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003006743,"about_ca_system_score_gemma":0.001310842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001841707,"about_ca_topic_score_gemma":0.003164256,"domain_scores_codex":[0.9992143,0.0001903159,0.00007497048,0.00009080057,0.0002922646,0.0001372945],"domain_scores_gemma":[0.9985523,0.0008393357,0.0001160727,0.00007765162,0.0002188351,0.0001958311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005566051,0.0001023447,0.0009824475,0.000127956,0.0000437347,0.004599667,0.0001337638,0.0001934912,0.005979396,0.0175101,0.9302964,0.0394742],"study_design_scores_gemma":[0.000361552,0.0001630743,0.001829041,0.00009133136,0.00004161725,0.003184291,0.000191233,0.0008791665,0.004557499,0.02797185,0.9606827,0.00004670121],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.002349635,0.006774351,0.0004431406,0.9502673,0.03346153,0.00002060356,0.00005741979,0.00006243575,0.006563607],"genre_scores_gemma":[0.04822024,0.007583125,0.001001582,0.8095504,0.09561329,0.0001307521,0.00006421977,0.00004448204,0.03779192],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01966349,"threshold_uncertainty_score":0.02181554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00895812567290441,"score_gpt":0.2312288586020774,"score_spread":0.222270732929173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}