{"id":"W4394935387","doi":"10.3310/yjwq4299","title":"Intravenous immunoglobulin treatment for encephalitis in children aged 6 months to 16 years: the IgNiTE RCT","year":2023,"lang":"en","type":"article","venue":"Efficacy and Mechanism Evaluation","topic":"Autoimmune Neurological Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Medical Research Council; Seqirus; University of Oxford; Action Medical Research; Great Ormond Street Hospital Charity; National Institute for Health and Care Research; Pfizer; National Institute for Health Research Health Protection Research Unit; National Institute for Social Care and Health Research; European Commission; Sanofi; Department of Health and Social Care; Moderna; CSL Behring; Public Health Agency; GlaxoSmithKline; Efficacy and Mechanism Evaluation Programme; Alexion Pharmaceuticals","keywords":"Medicine; Placebo; Encephalitis; Randomized controlled trial; Pediatrics; Clinical trial; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008391175,0.001089528,0.003372557,0.0009588735,0.0007892915,0.001677802,0.001186399,0.003510388,0.01021243],"category_scores_gemma":[0.01476191,0.0005384434,0.004298451,0.001252633,0.001272514,0.001478277,0.002055993,0.002951426,0.001179316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002038144,"about_ca_system_score_gemma":0.003529617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006329869,"about_ca_topic_score_gemma":0.01119713,"domain_scores_codex":[0.9917967,0.005933606,0.0006830206,0.000485896,0.0005420422,0.000558681],"domain_scores_gemma":[0.9946645,0.002392234,0.001362806,0.0005179077,0.000491241,0.00057134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5881804,0.004891225,0.05344522,0.1374447,0.03464888,0.001188683,0.002162257,0.001087814,0.002931206,0.005019141,0.03150533,0.1374952],"study_design_scores_gemma":[0.7682326,0.03257842,0.06747996,0.03691936,0.03484178,0.001080511,0.001459511,0.0005076987,0.0007530945,0.002897359,0.05305223,0.0001975666],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6601584,0.2670274,0.002267828,0.01590847,0.003771609,0.01739327,0.01201441,0.0003516758,0.02110687],"genre_scores_gemma":[0.9052354,0.04307825,0.006758692,0.0104984,0.001689271,0.02326899,0.004381349,0.00008739676,0.005002262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01021243,"threshold_uncertainty_score":0.04437727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04072338248257634,"score_gpt":0.326453919702195,"score_spread":0.2857305372196187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}