{"id":"W4394944574","doi":"10.1212/nxi.0000000000200222","title":"Vulnerability of Thalamic Nuclei at CSF Interface During the Entire Course of Multiple Sclerosis","year":2024,"lang":"en","type":"article","venue":"Neurology Neuroimmunology & Neuroinflammation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Mental Health; Medical Research Council; Canadian Institutes of Health Research; National Institute of Child Health and Human Development; University of California, San Diego; University of California, Los Angeles; National Institutes of Health; Université de Bordeaux; Agence Nationale de la Recherche; National Health and Medical Research Council; Commonwealth Scientific and Industrial Research Organisation; Alzheimer's Disease Neuroimaging Initiative; Centre National de la Recherche Scientifique; National Institute on Aging; Alzheimer's Association; Ministerio de Ciencia e Innovación; Northern California Institute for Research and Education; Michael J. Fox Foundation for Parkinson's Research","keywords":"Thalamus; Atrophy; Neurodegeneration; Neuroscience; Third ventricle; Multiple sclerosis; White matter; Medicine; Magnetic resonance imaging; Pathology; Psychology; Anatomy; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004511074,0.00036587,0.0007261168,0.0003141436,0.0002765933,0.00002022936,0.000439271,0.0002399562,0.0001591788],"category_scores_gemma":[0.001390474,0.0002750379,0.0003271667,0.0005280581,0.001578003,0.0002031655,0.0006949592,0.001138895,0.00006194365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006225611,"about_ca_system_score_gemma":0.00009796805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004553119,"about_ca_topic_score_gemma":0.00006317159,"domain_scores_codex":[0.9964113,0.0008549136,0.0009832128,0.0007809357,0.0004100344,0.0005595669],"domain_scores_gemma":[0.9965103,0.00164739,0.0003261129,0.001156236,0.0002917694,0.00006817411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001503672,0.0001858919,0.06134582,0.00050978,0.0002021536,0.00005133564,0.0005867941,0.0002074012,0.9296655,0.00005003551,0.0001640385,0.00552758],"study_design_scores_gemma":[0.001140548,0.0007333091,0.7674322,0.00008820303,0.00009846831,0.0002441992,0.00003513102,0.003886088,0.2255126,0.00002329811,0.0007015213,0.0001044632],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883986,0.001112973,0.0000131859,0.008075774,0.0008014083,0.001104028,0.00005918974,0.0002247759,0.0002100866],"genre_scores_gemma":[0.998134,0.001329846,0.00001560777,0.0001094747,0.00007852055,0.00006847938,0.00001811421,0.00006978646,0.0001761852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7060863,"threshold_uncertainty_score":0.9999702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03557527080217984,"score_gpt":0.2925264740360285,"score_spread":0.2569512032338487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}