{"id":"W4394964529","doi":"10.1016/j.phymed.2024.155616","title":"Paeoniflorin mitigates MMP-12 inflammation in silicosis via Yang-Yin-Qing-Fei Decoction in murine models","year":2024,"lang":"en","type":"article","venue":"Phytomedicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Science Foundation of Hebei Province; National Natural Science Foundation of China","keywords":"Paeoniflorin; Decoction; Traditional medicine; Inflammation; Matrix metalloproteinase; Medicine; Silicosis; Pharmacology; Chemistry; Immunology; Internal medicine; Pathology; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002322932,0.0006726515,0.0006021948,0.0005545418,0.0002398375,0.0002846634,0.0002749318,0.0005069152,0.001349541],"category_scores_gemma":[0.0001306271,0.0002092662,0.0005113066,0.0001811355,0.0003771434,0.0003762975,0.0001724243,0.001633405,0.0002120553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000171975,"about_ca_system_score_gemma":0.0003719213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008788396,"about_ca_topic_score_gemma":0.002066536,"domain_scores_codex":[0.9998528,0.00003107129,0.00001360004,0.00002164931,0.00003629614,0.00004456857],"domain_scores_gemma":[0.9999139,0.000007563391,0.00002192668,0.000007707405,0.00001035409,0.00003850231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005538633,0.002600862,0.0006154642,0.0004452539,0.00007712512,0.0002066934,0.00006460911,0.0003970212,0.9764335,0.0002398694,0.0004011845,0.01297976],"study_design_scores_gemma":[0.001725649,0.02285636,0.01541242,0.0001058656,0.0005342109,0.0004947245,0.0002728358,0.005744416,0.9446442,0.0005914778,0.007566642,0.00005114044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891376,0.003327949,0.004307871,0.0005133072,0.0002229166,0.0001404621,0.0004820547,0.0002581947,0.001609635],"genre_scores_gemma":[0.9920703,0.002120361,0.001872163,0.0001626828,0.00003002409,0.00009955275,0.000353396,0.00001773253,0.00327375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001349541,"threshold_uncertainty_score":0.004514635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138989786912795,"score_gpt":0.2673273761003926,"score_spread":0.2534283974091132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}