{"id":"W4394977656","doi":"10.1093/sleep/zsae067.0649","title":"0649 Samelisant Improves the Symptoms of Excessive Daytime Sleepiness in Narcolepsy: Results from a Phase-2 Study","year":2024,"lang":"en","type":"article","venue":"SLEEP","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Narcolepsy; Excessive daytime sleepiness; Daytime; Multiple Sleep Latency Test; Medicine; Psychology; Modafinil; Psychiatry; Sleep disorder; Insomnia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001416105,0.001201378,0.002124271,0.0003346294,0.0003440173,0.0007127173,0.0008428752,0.001431578,0.007952423],"category_scores_gemma":[0.0005532451,0.0003630157,0.001971836,0.0002832688,0.0006764728,0.0007086344,0.0002636877,0.001637247,0.001269854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005420085,"about_ca_system_score_gemma":0.0007723693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005650575,"about_ca_topic_score_gemma":0.002043883,"domain_scores_codex":[0.9996492,0.0001358217,0.00003081117,0.00007330528,0.00004194572,0.00006893241],"domain_scores_gemma":[0.9995957,0.00005431111,0.00007607234,0.00004347843,0.00005900584,0.0001715452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8181477,0.06798083,0.002812372,0.002304536,0.002976193,0.0002790527,0.0001590038,0.0005689827,0.04401668,0.0002006767,0.003734346,0.05681965],"study_design_scores_gemma":[0.5495785,0.4333849,0.01171066,0.00005962932,0.00109532,0.0001783244,0.00004479979,0.0003385898,0.001771614,0.00008690193,0.001714906,0.00003574586],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871505,0.004290931,0.0004931846,0.0003886146,0.0001956508,0.003539534,0.001986106,0.0001168535,0.00183848],"genre_scores_gemma":[0.9833651,0.003778214,0.001379137,0.0011042,0.0002300381,0.002964847,0.003078201,0.00002856294,0.004071733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007952423,"threshold_uncertainty_score":0.02660352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03782923889506148,"score_gpt":0.3433552643615455,"score_spread":0.305526025466484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}