{"id":"W4394977656","doi":"10.1093/sleep/zsae067.0649","title":"0649 Samelisant Improves the Symptoms of Excessive Daytime Sleepiness in Narcolepsy: Results from a Phase-2 Study","year":2024,"lang":"en","type":"article","venue":"SLEEP","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Narcolepsy; Excessive daytime sleepiness; Daytime; Multiple Sleep Latency Test; Medicine; Psychology; Modafinil; Psychiatry; Sleep disorder; Insomnia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006821507,0.0002373578,0.0003357066,0.0002868875,0.0001364133,0.0001847589,0.0009362045,0.00008149654,0.0001421709],"category_scores_gemma":[0.001207186,0.0001540752,0.0001051983,0.001357689,0.0002936186,0.0002908155,0.0003381609,0.0004870063,0.0001271939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006470357,"about_ca_system_score_gemma":0.00009645586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046264,"about_ca_topic_score_gemma":0.0001174397,"domain_scores_codex":[0.9967285,0.0004758677,0.0005977286,0.0008579777,0.0008449533,0.0004949312],"domain_scores_gemma":[0.9975764,0.001391076,0.0001063242,0.0007656155,0.00006411185,0.00009654073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002108573,0.004351877,0.002015736,0.0001059379,0.0001694249,0.001262003,0.02716321,0.0002571945,0.4401315,0.001340942,0.0007372709,0.5203563],"study_design_scores_gemma":[0.02752569,0.004718274,0.03717605,0.0009244473,0.0002807297,0.00003426963,0.01294346,0.129759,0.7682441,0.007210907,0.009525616,0.001657516],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947835,0.0004697656,0.00008030945,0.0007416439,0.0008045497,0.001068663,0.0004429118,0.00009629782,0.001512398],"genre_scores_gemma":[0.9991357,0.00002044264,0.000007970318,0.0001202811,0.0002057293,0.0002006992,0.00001549778,0.00003629928,0.0002573525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5186988,"threshold_uncertainty_score":0.6283004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03782923889506148,"score_gpt":0.3433552643615455,"score_spread":0.305526025466484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}