{"id":"W4394981645","doi":"10.1016/j.eclinm.2024.102604","title":"Guideline for the management of Clostridioides difficile infection in pediatric patients with cancer and hematopoietic cell transplantation recipients: 2024 update","year":2024,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; University of Toronto; Hospital for Sick Children; Pediatric Oncology Group","funders":"Canadian Institutes of Health Research; U.S. Food and Drug Administration; National Institutes of Health; Pediatric Oncology Group of Ontario; Abramson Cancer Center; Centers for Disease Control and Prevention; Canada Research Chairs; Astellas Pharma US","keywords":"Medicine; Guideline; Fidaxomicin; Clostridioides; Intensive care medicine; Metronidazole; Vancomycin; Transplantation; Internal medicine; Randomized controlled trial; Hematopoietic stem cell transplantation; Population; Hematopoietic cell; Clostridium difficile; Antibiotics; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003557357,0.001206591,0.002279642,0.003413565,0.0005888694,0.001536687,0.003423919,0.005680052,0.008130522],"category_scores_gemma":[0.01533573,0.0008046098,0.002823195,0.002765792,0.0004509662,0.001625234,0.001273117,0.005263124,0.006326295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002322095,"about_ca_system_score_gemma":0.007889409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01803559,"about_ca_topic_score_gemma":0.03370632,"domain_scores_codex":[0.9959637,0.001201693,0.001211693,0.0001795256,0.001257385,0.0001860462],"domain_scores_gemma":[0.9848989,0.00352638,0.002242203,0.0002666545,0.008344744,0.0007212757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000598802,0.00009582216,0.0005937322,0.004969999,0.0001248562,0.0002933923,0.00008472033,0.000359953,0.0003072825,0.0008728481,0.8220395,0.1701979],"study_design_scores_gemma":[0.0002661643,0.0001078826,0.00367599,0.03057034,0.0004262608,0.001137701,0.00007702949,0.0004560842,0.0002484016,0.001462759,0.9615172,0.00005411355],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.003482801,0.5221729,0.02435988,0.3055161,0.0268458,0.004396454,0.02584899,0.002655654,0.08472149],"genre_scores_gemma":[0.01475058,0.5840636,0.1291144,0.1698267,0.01192998,0.00774276,0.03974002,0.0005797038,0.04225234],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01803559,"threshold_uncertainty_score":0.03586119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110359361786224,"score_gpt":0.3351017073786902,"score_spread":0.313998113760828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}