{"id":"W4394989475","doi":"10.1007/s00128-024-03896-9","title":"Toxicogenomics of Five Cytostatics in Fathead Minnow (Pimephales promelas) Larvae","year":2024,"lang":"en","type":"article","venue":"Bulletin of Environmental Contamination and Toxicology","topic":"Pharmaceutical and Antibiotic Environmental Impacts","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministère de l’Environnement, de la Lutte contre les changements climatiques, de la Faune et des Parcs; Ministère des Ressources naturelles et des Forêts; Institut National de la Recherche Scientifique","funders":"Canada Research Chairs","keywords":"Pimephales promelas; Minnow; Biology; Ifosfamide; Toxicogenomics; Toxicity; Cyclophosphamide; Toxicology; Pharmacology; Internal medicine; Gene; Genetics; Gene expression; Medicine; Fish <Actinopterygii>; Chemotherapy; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005158945,0.0002166052,0.0001584994,0.0002812355,0.0001827011,0.0002141289,0.00008261942,0.0002049723,0.0006707198],"category_scores_gemma":[0.00008613953,0.00007834176,0.0002517418,0.0001749177,0.0001086258,0.00009823504,0.0001252725,0.0002456403,0.0001058517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003174029,"about_ca_system_score_gemma":0.0002447428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003191016,"about_ca_topic_score_gemma":0.004806914,"domain_scores_codex":[0.999948,0.000003294459,0.000002486252,0.00001525959,0.00001861617,0.00001235373],"domain_scores_gemma":[0.9999466,0.000006630957,0.00001449437,0.000002671143,0.00001968116,0.000009867046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001869531,0.00001669825,0.004241298,0.00002480469,0.00001607635,0.00003479463,0.00001879425,0.000128323,0.9933817,0.00002257786,0.00003373293,0.001894151],"study_design_scores_gemma":[0.00001319242,0.0007961133,0.2404219,0.00001249221,0.0001485294,0.0002421698,0.0002238607,0.001576655,0.7545517,0.00007479246,0.001924793,0.00001380184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979898,0.0003126301,0.000328446,0.00003417599,0.000004650442,0.00001015637,0.0007858162,0.00001318857,0.0005211882],"genre_scores_gemma":[0.9937449,0.0005489421,0.0007242185,0.00008162916,0.00000400026,0.00002568879,0.001395827,0.00001196475,0.003462825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003191016,"threshold_uncertainty_score":0.006344914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01165372969423878,"score_gpt":0.2513711280017235,"score_spread":0.2397173983074847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}