{"id":"W4394992983","doi":"10.1007/s12035-024-04185-6","title":"Ultra-Low-Dose UV-C Photo-stimulation Promotes Neural Stem Cells Differentiation via Presenilin 1 Mediated Notch and β-Catenin Activation","year":2024,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Neurogenesis; Neural stem cell; Presenilin; Stimulation; Stem cell; Cell biology; Notch signaling pathway; Neuroscience; Chemistry; Biology; Biophysics; Signal transduction; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008338528,0.0001993691,0.0001584559,0.0001998444,0.0001325549,0.0002415221,0.0001427344,0.0002331372,0.002026464],"category_scores_gemma":[0.00007108201,0.0001246564,0.0002241414,0.0001207292,0.0001798024,0.0001662959,0.0001631792,0.0005650198,0.0002517008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002607285,"about_ca_system_score_gemma":0.0002306967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007899228,"about_ca_topic_score_gemma":0.001805058,"domain_scores_codex":[0.9999305,0.000007104562,0.000006127705,0.00001631937,0.00001985799,0.00002008804],"domain_scores_gemma":[0.9999412,0.0000158169,0.00001325029,0.000007321542,0.000006340099,0.00001605198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005779295,0.0000112756,0.000061099,0.0000227187,0.000002124749,0.00002224995,0.000008742873,0.00001713663,0.9991216,0.00006747615,0.00002914916,0.0005786313],"study_design_scores_gemma":[0.000005682916,0.00005172822,0.003297602,0.000004565316,0.000006509422,0.0000833314,0.00002322315,0.0001868425,0.9954755,0.00004129273,0.000821333,0.000002344467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927298,0.001729343,0.00193356,0.0001109976,0.00004259915,0.0000227869,0.0002701429,0.00007803953,0.003082675],"genre_scores_gemma":[0.9944656,0.0008088266,0.001298456,0.0000670446,0.000007789872,0.00002968819,0.0002129844,0.00001412094,0.003095495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002026464,"threshold_uncertainty_score":0.006779194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02417621653586104,"score_gpt":0.2767450130423856,"score_spread":0.2525687965065246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}