{"id":"W4395008759","doi":"10.3389/fimmu.2024.1375461","title":"Fructose-induced metabolic reprogramming of cancer cells","year":2024,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Cancer cell; Cancer; Fructose; Reprogramming; Biology; Malignancy; Cancer research; Bioinformatics; Biochemistry; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001782796,0.0004322957,0.0004508634,0.000883529,0.0001566541,0.0006169468,0.0002968821,0.0004773071,0.00216162],"category_scores_gemma":[0.0001786985,0.0001067764,0.0002760484,0.0006696233,0.0001780067,0.0005111631,0.0004922391,0.0007295092,0.001020982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003777881,"about_ca_system_score_gemma":0.0003353489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004627595,"about_ca_topic_score_gemma":0.0007694649,"domain_scores_codex":[0.9999419,0.000009946039,0.000005231356,0.00001208529,0.00001988916,0.00001088018],"domain_scores_gemma":[0.9999633,0.00001162866,0.000005548364,0.000001591655,0.00001182975,0.000006129455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000113483,0.00007342306,0.0002822526,0.01056814,0.00007419871,0.0003114749,0.00007928447,0.0004311901,0.02110124,0.008297705,0.02304137,0.9356261],"study_design_scores_gemma":[0.00001108796,0.00009205277,0.001256877,0.001158101,0.00005721948,0.0009680636,0.00005047651,0.0001160765,0.005180732,0.002648186,0.9884444,0.00001667818],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009249104,0.9947424,0.000405403,0.0003692734,0.0003108399,0.000007650537,0.00006472503,0.00001962833,0.003155042],"genre_scores_gemma":[0.00381709,0.9940251,0.0002371881,0.0002129479,0.0001443621,0.000008456482,0.0001024316,0.000002760653,0.001449837],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00216162,"threshold_uncertainty_score":0.007231355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03405729949132664,"score_gpt":0.3560519874829098,"score_spread":0.3219946879915832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}