{"id":"W4395009911","doi":"10.3390/cancers16081600","title":"Signaling by Type I Interferons in Immune Cells: Disease Consequences","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Canada Research Chairs; University Health Network","funders":"National Cancer Institute; National Institutes of Health","keywords":"Immune system; Tumor microenvironment; Cancer research; Interferon; Signal transduction; Tumor progression; Biology; Cancer; Immunology; Cancer cell; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002375372,0.0003096469,0.0003546944,0.0002510815,0.0001651725,0.0005806122,0.0001993184,0.0004536391,0.0006783796],"category_scores_gemma":[0.0001465133,0.00006882894,0.0001731181,0.0002661069,0.0002901957,0.0004651082,0.000213444,0.0005632819,0.0004090175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353599,"about_ca_system_score_gemma":0.0001935524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007970181,"about_ca_topic_score_gemma":0.0001597227,"domain_scores_codex":[0.9999136,0.00002312694,0.000009422184,0.0000130511,0.00002701431,0.00001382476],"domain_scores_gemma":[0.9999442,0.00002143689,0.00001312492,0.000002360725,0.00001020887,0.000008619747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004567143,0.00007415952,0.002771579,0.00602729,0.0001035041,0.001871279,0.0003794433,0.001001413,0.2495787,0.02122985,0.01550905,0.700997],"study_design_scores_gemma":[0.00002076804,0.0005873978,0.007368833,0.001632483,0.0001679242,0.009192283,0.0004583044,0.0005069857,0.04973967,0.0158761,0.9144139,0.00003549269],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008749241,0.9847856,0.001445798,0.001179072,0.0008691534,0.000004900695,0.0000273512,0.00001871479,0.002920165],"genre_scores_gemma":[0.03334904,0.9615173,0.0008164715,0.0006692295,0.001015889,0.000008877256,0.0000353572,0.000005324482,0.002582568],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0006783796,"threshold_uncertainty_score":0.002269447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376948333833853,"score_gpt":0.2641355772435333,"score_spread":0.2503660939051948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}