{"id":"W4395026319","doi":"10.1016/j.clim.2024.110024","title":"82 Newborn Screening for Severe Combined Immune Deficiency: The Canadian Landscape","year":2024,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University of Saskatchewan; Hospital for Sick Children; University of Manitoba; University of Calgary; Saskatchewan Health Authority; Dalhousie University; University of Toronto; Izaak Walton Killam Health Centre; Saskatchewan Health; BC Children's Hospital; University of Alberta","funders":"","keywords":"Immune system; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001841298,0.0003728051,0.0006266758,0.00024041,0.001503257,0.0001406753,0.001126116,0.0008991141,0.00086873],"category_scores_gemma":[0.0007551234,0.0002687364,0.0006059646,0.0004870802,0.001381168,0.0001527437,0.0001979554,0.001451878,0.001534987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006101671,"about_ca_system_score_gemma":0.000790104,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008727816,"about_ca_topic_score_gemma":0.00372076,"domain_scores_codex":[0.996491,0.00046668,0.001103835,0.0007005657,0.00004775792,0.001190235],"domain_scores_gemma":[0.9969262,0.001897214,0.0001516725,0.000845799,0.0001530716,0.00002605161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001131952,0.0005019106,0.002122996,0.00009027392,0.002346545,0.00003648095,0.001668525,0.00008653186,0.01538545,0.05786002,0.02440419,0.8943651],"study_design_scores_gemma":[0.002561084,0.0007601553,0.02163639,0.00009699696,0.0002244053,0.0001680174,0.001013833,0.0003976231,0.0005033581,0.002480596,0.9696633,0.0004942891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.207857,0.6932009,0.007663552,0.03218703,0.0301064,0.00314501,0.0003810393,0.00124012,0.02421886],"genre_scores_gemma":[0.9905028,0.000566151,0.000196856,0.001333164,0.00003780627,0.0001463724,0.0004394704,0.0000603164,0.006717063],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9452591,"threshold_uncertainty_score":0.9999765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426489897979251,"score_gpt":0.3091758178387783,"score_spread":0.2749109188589858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}