{"id":"W4395031644","doi":"10.12688/f1000research.138354.2","title":"Validation and in vivo characterization of research antibodies for Moesin, CD44, Midkine, and sFRP-1.","year":2024,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Genome Canada; Ontario Genomics; Mitacs; Government of Canada; National Institute on Aging; Emory University","keywords":"Midkine; In vivo; Moesin; Open peer review; Antibody; Biology; Computational biology; Medicine; Plant biology; Neuroscience; Immunology; Biochemistry; Cytoskeleton; Biotechnology; Cell; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002082244,0.001307341,0.0003746302,0.0009815875,0.0004019837,0.0004724505,0.0006536398,0.0008093127,0.003353632],"category_scores_gemma":[0.001327747,0.0004423983,0.0007693354,0.0005085194,0.0002976845,0.0004355232,0.0002868875,0.00102145,0.001726017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008074628,"about_ca_system_score_gemma":0.0003968182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009084992,"about_ca_topic_score_gemma":0.001799614,"domain_scores_codex":[0.9986499,0.0002576771,0.0002064329,0.0002757631,0.0003648675,0.0002453701],"domain_scores_gemma":[0.9983961,0.0002824264,0.0003272702,0.0002446447,0.0005962937,0.0001532809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001156408,0.00007917644,0.0001656927,0.00005700451,0.00001096416,0.00002487063,0.00002272572,0.00005182896,0.9976822,0.0001032173,0.0001961131,0.001490604],"study_design_scores_gemma":[0.00005231483,0.0006346957,0.003446898,0.00002326394,0.00005081797,0.0005158549,0.00002122131,0.0008736976,0.9859396,0.00005169617,0.008382347,0.000007569614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8631768,0.00554316,0.1106279,0.000950079,0.0003076617,0.002034411,0.006581279,0.0008105914,0.009968082],"genre_scores_gemma":[0.7761126,0.005222026,0.1653114,0.0007590229,0.0001459277,0.002556747,0.02922052,0.0005021514,0.02016969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003353632,"threshold_uncertainty_score":0.01121902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0507484388257423,"score_gpt":0.391767174130469,"score_spread":0.3410187353047267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}