{"id":"W4395031644","doi":"10.12688/f1000research.138354.2","title":"Validation and in vivo characterization of research antibodies for Moesin, CD44, Midkine, and sFRP-1.","year":2024,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Genome Canada; Ontario Genomics; Mitacs; Government of Canada; National Institute on Aging; Emory University","keywords":"Midkine; In vivo; Moesin; Open peer review; Antibody; Biology; Computational biology; Medicine; Plant biology; Neuroscience; Immunology; Biochemistry; Cytoskeleton; Biotechnology; Cell; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002637513,0.0002346986,0.0003421638,0.0008256957,0.000109689,0.0001877125,0.0003598583,0.0005015405,0.0000224593],"category_scores_gemma":[0.0005550078,0.0002263001,0.00006824626,0.0003400758,0.0005469858,0.000008218356,0.002414548,0.0007712702,0.000002333155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004521528,"about_ca_system_score_gemma":0.0004639735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003309691,"about_ca_topic_score_gemma":0.0001262618,"domain_scores_codex":[0.9971158,0.0003456094,0.0004099027,0.0008988187,0.000639817,0.0005900742],"domain_scores_gemma":[0.9984556,0.0001262092,0.00006704905,0.0005116577,0.0007050201,0.0001344147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005307453,0.00006988432,0.003606347,0.002963719,0.00006095396,0.00000754654,0.0001709678,0.000008370977,0.9876336,0.0002907938,0.0009774675,0.003679614],"study_design_scores_gemma":[0.0006701164,0.0005047935,0.01064084,0.0006028679,0.00001518203,0.00000942488,0.0001173918,0.001825737,0.9728658,0.00558578,0.006858855,0.0003031798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923561,0.003028512,0.0002553224,0.0009010092,0.000107562,0.00210078,0.000849153,0.00001252291,0.0003890463],"genre_scores_gemma":[0.9862917,0.00779395,0.0005469674,0.00001184803,0.0003087796,0.0006181819,0.0008442029,0.00007047417,0.003513877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01476776,"threshold_uncertainty_score":0.922825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0507484388257423,"score_gpt":0.391767174130469,"score_spread":0.3410187353047267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}