{"id":"W4395040894","doi":"10.1161/circ.126.suppl_21.a19535","title":"Abstract 19535: Constitutive Expression of a Dominant Negative TGF-β Type-II Receptor in the Posterior Left Atrium Attenuates NADPH Oxidase and Mitochondrial Superoxide Production and Decreases Atrial Fibrosis (Resulting in Decreased AF)","year":2012,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brandon University","funders":"","keywords":"Medicine; Superoxide; NADPH oxidase; Left atrium; Receptor; Fibrosis; Internal medicine; Transforming growth factor; Cardiology; Endocrinology; Right atrium; Oxidative stress; Atrial fibrillation; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002410249,0.0005344435,0.0004994851,0.0003094669,0.0001794145,0.0004029642,0.0002980056,0.0005511966,0.00464846],"category_scores_gemma":[0.0001279235,0.0002703977,0.0003911891,0.0001528104,0.0006061906,0.0003768895,0.0001533799,0.00132527,0.001190692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003591774,"about_ca_system_score_gemma":0.0003902469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006683771,"about_ca_topic_score_gemma":0.0009457186,"domain_scores_codex":[0.9997106,0.00002834669,0.00003368886,0.00007374355,0.00008842629,0.00006515559],"domain_scores_gemma":[0.9997647,0.00002546737,0.00008774307,0.00001582319,0.00001415757,0.0000921071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003940816,0.0001054131,0.0001233966,0.00006343034,0.000007844325,0.00004730531,0.00002028313,0.00003028409,0.9981098,0.0001172578,0.000157955,0.0008228859],"study_design_scores_gemma":[0.0004485816,0.005458514,0.005396958,0.00003621457,0.00009962316,0.0007248199,0.0001001786,0.001302885,0.9786032,0.00008969296,0.007724963,0.00001438513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901608,0.001681258,0.004002733,0.0004946169,0.000148382,0.0001047638,0.001120479,0.0002550845,0.002031715],"genre_scores_gemma":[0.9809127,0.00129968,0.006406497,0.0002340705,0.00007885522,0.0002340154,0.00184646,0.00007799706,0.008909631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00464846,"threshold_uncertainty_score":0.01555061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02031718486600307,"score_gpt":0.2696650649293343,"score_spread":0.2493478800633312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}