{"id":"W4395063540","doi":"10.1016/j.clim.2024.110038","title":"96 Molecular and functional identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutation","year":2024,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"FOXP3; Identification (biology); Effector; Mutation; Biology; Computational biology; Genetics; Immunology; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003546939,0.0001402733,0.0002966638,0.0001872036,0.00005489751,0.00001856751,0.00004566383,0.000314344,0.0001235453],"category_scores_gemma":[0.00008692559,0.0001190694,0.0000533821,0.0001163829,0.0004079613,0.0002220169,0.00004446475,0.0003878154,0.00006437848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004657125,"about_ca_system_score_gemma":0.00003904084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003099451,"about_ca_topic_score_gemma":0.000005876062,"domain_scores_codex":[0.9986133,0.0003351054,0.0004784098,0.0003763353,0.00003938433,0.0001574742],"domain_scores_gemma":[0.9990895,0.0004020117,0.0002219459,0.0001711094,0.0001017895,0.00001357472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002941521,0.0005545835,0.1325773,0.0001023507,0.0008051189,0.000009504657,0.0004446877,0.00001468365,0.8476215,0.0007629747,0.0008456293,0.01332018],"study_design_scores_gemma":[0.002179619,0.0005645492,0.8475353,0.00009618812,0.00007653982,0.00001511383,0.0002273388,0.00003714357,0.1480993,0.00009957411,0.0009451734,0.0001241484],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942433,0.002124069,0.0004563114,0.00006905614,0.002714726,0.0002785325,0.00000893062,0.00004370345,0.00006136147],"genre_scores_gemma":[0.9988463,0.00009351892,0.00001334754,0.0000471298,0.00001064086,0.0000247043,0.0001775962,0.00001539658,0.0007713523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.714958,"threshold_uncertainty_score":0.4855508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257780466846776,"score_gpt":0.2574514668599689,"score_spread":0.2448736621915012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}