{"id":"W4395068276","doi":"10.1182/blood.2023023153","title":"How I treat Philadelphia chromosome–like acute lymphoblastic leukemia in children, adolescents, and young adults","year":2024,"lang":"en","type":"review","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute","keywords":"Medicine; Clinical trial; Oncology; Philadelphia chromosome; Population; Internal medicine; Adverse effect; Acute lymphocytic leukemia; Pediatrics; Lymphoblastic Leukemia; Leukemia; Biology; Genetics; Chromosomal translocation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007236269,0.0005367842,0.0009032683,0.001616413,0.0002545427,0.0009494568,0.000648754,0.001477631,0.003105093],"category_scores_gemma":[0.001900764,0.0001692506,0.0006085928,0.0009562105,0.0003440562,0.001228179,0.0005522136,0.002068821,0.001578094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005209057,"about_ca_system_score_gemma":0.001102733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001155142,"about_ca_topic_score_gemma":0.002372127,"domain_scores_codex":[0.9996753,0.0001064316,0.00006374375,0.00004163611,0.00008997569,0.00002298027],"domain_scores_gemma":[0.9994417,0.0003180498,0.00009224636,0.00001022247,0.0001049231,0.00003287311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001024969,0.00004954827,0.0001409689,0.02747333,0.0001390975,0.0001472076,0.00007981511,0.0001660127,0.0004987872,0.003021559,0.06212399,0.9060573],"study_design_scores_gemma":[0.00005335528,0.0001080611,0.0006373462,0.0310528,0.0002641508,0.001165107,0.000111358,0.00006125492,0.0001727996,0.001973837,0.9643832,0.00001673288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006031054,0.9974625,0.0000628402,0.001155527,0.000482965,0.000008505867,0.00001533687,0.000006579271,0.0007453263],"genre_scores_gemma":[0.0005725889,0.997254,0.0001969246,0.001251082,0.0003279059,0.00001198026,0.00002146019,0.000001796091,0.00036228],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003105093,"threshold_uncertainty_score":0.0103876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01452320910908536,"score_gpt":0.2804288934406625,"score_spread":0.2659056843315771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}