{"id":"W4395068743","doi":"10.1021/acs.chemrev.3c00819","title":"Small-Molecule Fluorescent Probes for Binding- and Activity-Based Sensing of Redox-Active Biological Metals","year":2024,"lang":"en","type":"review","venue":"Chemical Reviews","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Australian Research Council; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; National Institutes of Health; University of Sydney; Agilent Technologies","keywords":"Chemistry; Redox; Fluorescence; Nanotechnology; Metal; Transition metal; Combinatorial chemistry; Biochemistry; Inorganic chemistry; Catalysis; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008209011,0.001419814,0.001282762,0.002060351,0.0002847589,0.0007885589,0.001580574,0.001727582,0.003057815],"category_scores_gemma":[0.0006577969,0.000552061,0.0007258336,0.001713909,0.0006666956,0.001471803,0.0008010883,0.002637322,0.003535448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001079462,"about_ca_system_score_gemma":0.000615924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007492815,"about_ca_topic_score_gemma":0.001111215,"domain_scores_codex":[0.9995689,0.00006364172,0.00002176929,0.00007823201,0.0002039285,0.00006358894],"domain_scores_gemma":[0.9998201,0.00007873508,0.00002447308,0.000009472375,0.00004925518,0.00001805518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001125731,0.0002522179,0.0001874582,0.0257263,0.000150535,0.0005056956,0.0001867142,0.001731756,0.1434982,0.02426442,0.04380866,0.7595755],"study_design_scores_gemma":[0.00001747791,0.0002016403,0.0004244779,0.0009628792,0.00006545929,0.0009621006,0.00003648849,0.0004251451,0.02918442,0.001993795,0.9656836,0.00004251733],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008740218,0.9902838,0.003428853,0.0003288822,0.0005638708,0.0000379251,0.00005529184,0.00008620758,0.004341227],"genre_scores_gemma":[0.0064114,0.9852556,0.003057404,0.0004402506,0.0001974984,0.00009532816,0.0001341842,0.00001338525,0.004394939],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003057815,"threshold_uncertainty_score":0.01022941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1297408504014816,"score_gpt":0.3484382333182356,"score_spread":0.218697382916754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}