{"id":"W4395115264","doi":"10.3389/fnagi.2024.1345251","title":"A 3D pseudo-continuous arterial spin labeling study of altered cerebral blood flow correlation networks in mild cognitive impairment and Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Advanced MRI Techniques and Applications","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Natural Science Foundation of Liaoning Province; Eisai; Fundamental Research Funds for the Central Universities; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Cerebral blood flow; Arterial spin labeling; Correlation; Cardiology; Cognitive impairment; Cognition; Disease; Medicine; Neuroscience; Internal medicine; Psychology; Mathematics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003299042,0.0001981445,0.0001615903,0.0007164774,0.0002299487,0.0002653651,0.0001540399,0.0002210192,0.000653392],"category_scores_gemma":[0.0009067558,0.0001811267,0.0001532856,0.0004062262,0.0002815328,0.0002923913,0.0001985464,0.0001514694,0.00007657857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776186,"about_ca_system_score_gemma":0.0002222665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004603306,"about_ca_topic_score_gemma":0.00498873,"domain_scores_codex":[0.9999338,0.00001807403,0.000003610689,0.00001677418,0.00001410032,0.0000137202],"domain_scores_gemma":[0.9998013,0.00005879568,0.00006117849,0.00001810909,0.00002815318,0.0000325634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005359555,0.000463845,0.476639,0.0004422322,0.0005881673,0.005921846,0.002247428,0.009502535,0.3953651,0.002268717,0.001214235,0.09998728],"study_design_scores_gemma":[0.00004775388,0.0003673478,0.9700649,0.00001140534,0.00007038047,0.002327082,0.0003386914,0.01878553,0.005995336,0.001310136,0.0006605183,0.00002090211],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970794,0.0001562153,0.002420375,0.0000232728,0.000001956867,0.00001128734,0.00007831764,0.0000153844,0.0002139572],"genre_scores_gemma":[0.9981286,0.00008609477,0.001525252,0.00001003218,0.000005374728,0.0000150623,0.0001039928,0.000002974194,0.0001226586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004603306,"threshold_uncertainty_score":0.009153008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01665149470178728,"score_gpt":0.2978368355801019,"score_spread":0.2811853408783146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}