{"id":"W4395456557","doi":"10.1002/bit.28723","title":"Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance","year":2024,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Bayer HealthCare","keywords":"Chinese hamster ovary cell; Ovary; Biology; Chemistry; Chromatography; Andrology; Cell culture; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184737,0.0002085609,0.0001351255,0.0001467183,0.00009528522,0.00005212356,0.0001334614,0.0003368937,0.00001395916],"category_scores_gemma":[0.00001327476,0.0001708764,0.00006613178,0.000208185,0.00003767878,0.000009522031,0.0002371016,0.0001933672,0.00001748946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000112461,"about_ca_system_score_gemma":0.00002013883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008357422,"about_ca_topic_score_gemma":0.000001926819,"domain_scores_codex":[0.9990289,0.00001326425,0.0001479719,0.0004635525,0.00005809074,0.0002882219],"domain_scores_gemma":[0.9996068,0.000009991421,0.00001427555,0.0002615983,0.00001724603,0.00009009637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002431535,0.00001630696,0.001253187,0.0001430924,0.00004092384,0.000009031993,0.00002379159,0.0001827841,0.9800539,0.00005369083,0.000652125,0.01754688],"study_design_scores_gemma":[0.0001830459,0.0004586846,0.0009548924,0.00006145731,0.000020952,0.00005984093,0.0000263759,0.006946694,0.9550541,0.00002960841,0.0358807,0.0003236411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587709,0.004346804,0.03503415,0.0006540947,0.0005812129,0.0001530544,0.00001825444,0.0002096789,0.0002318144],"genre_scores_gemma":[0.9939939,0.0004140775,0.004633169,0.0002151207,0.0002456816,0.00004189121,0.00001587829,0.00003107448,0.0004091898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03522858,"threshold_uncertainty_score":0.6968139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003615325534541497,"score_gpt":0.2380824004494569,"score_spread":0.2344670749149154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}