{"id":"W4395456557","doi":"10.1002/bit.28723","title":"Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance","year":2024,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Bayer HealthCare","keywords":"Chinese hamster ovary cell; Ovary; Biology; Chemistry; Chromatography; Andrology; Cell culture; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006600991,0.0007309619,0.0007473543,0.0007084831,0.0003041458,0.0007646686,0.0008851519,0.000495032,0.001985347],"category_scores_gemma":[0.0004874401,0.0003062869,0.0005711858,0.0004571865,0.0002044648,0.000525513,0.0006208689,0.00110837,0.001998831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003857689,"about_ca_system_score_gemma":0.0004151491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001257136,"about_ca_topic_score_gemma":0.002376587,"domain_scores_codex":[0.99931,0.00007905923,0.00009788587,0.00011536,0.0003293732,0.00006823584],"domain_scores_gemma":[0.9994994,0.00009403146,0.00008396264,0.00009054264,0.0001751164,0.0000567766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002562027,0.00002594352,0.0001509934,0.00004478685,0.00000663939,0.00005104143,0.00002884072,0.0000643028,0.9964479,0.0001309076,0.000224583,0.002798286],"study_design_scores_gemma":[0.000004441021,0.0001249668,0.0008506662,0.000006316709,0.00002447076,0.0001614359,0.00001614821,0.00141251,0.9910517,0.00003690167,0.006296678,0.00001378531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7410952,0.004058999,0.2346547,0.0005148067,0.0005017148,0.0008209456,0.002531284,0.003649503,0.01217285],"genre_scores_gemma":[0.7151794,0.004403159,0.2406451,0.0004566406,0.00009559948,0.001221032,0.009766387,0.001309724,0.02692297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001985347,"threshold_uncertainty_score":0.006641626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003615325534541497,"score_gpt":0.2380824004494569,"score_spread":0.2344670749149154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}