{"id":"W4395465087","doi":"10.1007/s11105-024-01459-0","title":"Development of a Csy4-Processing TRV-Based CRISPR/Cas9 Genome Editing System in Nicotiana benthamiana","year":2024,"lang":"en","type":"article","venue":"Plant Molecular Biology Reporter","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; National Natural Science Foundation of China","keywords":"Nicotiana benthamiana; CRISPR; Biology; Genome editing; Cas9; Computational biology; Genome; Guide RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002990062,0.0005566497,0.0005090352,0.0003692662,0.0002749125,0.0004564849,0.0009236817,0.0005551819,0.0009159035],"category_scores_gemma":[0.0001398437,0.0003294544,0.0004868223,0.0002469984,0.000238361,0.0002985582,0.000433447,0.0009938371,0.0009558389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006398473,"about_ca_system_score_gemma":0.000399316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002191449,"about_ca_topic_score_gemma":0.002578869,"domain_scores_codex":[0.9996778,0.00003150735,0.00004086085,0.00009366826,0.0001170557,0.00003914682],"domain_scores_gemma":[0.9998906,0.00001003889,0.00003142648,0.00001742786,0.00002191162,0.00002852752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001351189,0.00001093182,0.00005714061,0.00003160399,0.000004886076,0.000031811,0.000009612179,0.000125032,0.9981318,0.0001027073,0.00004549073,0.001435434],"study_design_scores_gemma":[0.00001200512,0.0001094887,0.0007546317,0.000006026796,0.0000208117,0.0002078791,0.00001663251,0.003378071,0.9893699,0.00004599658,0.006063217,0.00001541338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7692414,0.002016283,0.2153165,0.000406105,0.0002409025,0.0007862605,0.00223828,0.004148792,0.005605496],"genre_scores_gemma":[0.8434213,0.001277954,0.1338993,0.000133026,0.00002287579,0.0003883091,0.004911017,0.0003330786,0.01561304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002191449,"threshold_uncertainty_score":0.004642367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008568074725878604,"score_gpt":0.284130632212001,"score_spread":0.2755625574861224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}