{"id":"W4395469681","doi":"10.1097/shk.0000000000002362","title":"INHIBITORS OF INORGANIC POLYPHOSPHATE AND NUCLEIC ACIDS ATTENUATE IN VITRO THROMBIN GENERATION IN PLASMA FROM TRAUMA PATIENTS","year":2024,"lang":"en","type":"article","venue":"Shock","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; National Heart, Lung, and Blood Institute; Georgia Clinical and Translational Science Alliance","keywords":"Polyphosphate; In vitro; Nucleic acid; Chemistry; Thrombin; Thrombin generation; Biochemistry; Pharmacology; Medicine; Platelet; Immunology; Phosphate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001082936,0.0002282597,0.0002253641,0.0001258038,0.0000746349,0.0002016943,0.00009038247,0.0001306082,0.001287245],"category_scores_gemma":[0.0005565404,0.0000776428,0.0001249048,0.00009628091,0.00007602698,0.00007215966,0.0001185007,0.0002938193,0.0001809247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001169974,"about_ca_system_score_gemma":0.0001390422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003141258,"about_ca_topic_score_gemma":0.0002760171,"domain_scores_codex":[0.9999238,0.00001641242,0.00001007891,0.0000154115,0.00001874965,0.00001550198],"domain_scores_gemma":[0.999815,0.00003792373,0.00008392766,0.000008383066,0.00001422692,0.00004061745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04682199,0.001943154,0.2118194,0.0005053297,0.0005899356,0.001038266,0.0004143478,0.0009313734,0.5981116,0.0001444192,0.001545059,0.1361351],"study_design_scores_gemma":[0.00111315,0.04389521,0.802305,0.00005287489,0.0005105456,0.005733085,0.0003039325,0.002758525,0.1377673,0.000149096,0.005389917,0.00002129801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987613,0.0007036077,0.0001979466,0.00002900424,0.000006055346,0.00001163074,0.00007487569,0.00001169266,0.0002039594],"genre_scores_gemma":[0.9988819,0.0002627996,0.0002949065,0.00003456236,0.00001098267,0.00001940602,0.000172229,0.000002151966,0.0003211127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001287245,"threshold_uncertainty_score":0.004306257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353702481432531,"score_gpt":0.2405446776307807,"score_spread":0.2270076528164554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}