{"id":"W4395469681","doi":"10.1097/shk.0000000000002362","title":"INHIBITORS OF INORGANIC POLYPHOSPHATE AND NUCLEIC ACIDS ATTENUATE IN VITRO THROMBIN GENERATION IN PLASMA FROM TRAUMA PATIENTS","year":2024,"lang":"en","type":"article","venue":"Shock","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; National Heart, Lung, and Blood Institute; Georgia Clinical and Translational Science Alliance","keywords":"Polyphosphate; In vitro; Nucleic acid; Chemistry; Thrombin; Thrombin generation; Biochemistry; Pharmacology; Medicine; Platelet; Immunology; Phosphate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224724,0.0001759164,0.0003478762,0.0002357486,0.00002744525,0.00002973559,0.00005201623,0.0001303357,0.00009143719],"category_scores_gemma":[0.00003979196,0.0001664325,0.00006107123,0.000401344,0.00005600245,0.0001877543,0.00003958962,0.0001577095,0.0000220095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00010193,"about_ca_system_score_gemma":0.00006573728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009806876,"about_ca_topic_score_gemma":0.0004734266,"domain_scores_codex":[0.9986844,0.00003728999,0.0004807982,0.0003490378,0.0002238571,0.0002245874],"domain_scores_gemma":[0.9996046,0.00005388141,0.00006120794,0.0001652643,0.00003442583,0.00008057462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004188193,0.0003634213,0.5783686,0.0002066061,0.00009289926,0.00005753107,0.006842788,0.00002818984,0.3118408,0.0001787617,0.001004915,0.1005966],"study_design_scores_gemma":[0.002699816,0.0001853999,0.6033744,0.000303309,0.00005299614,0.000004533602,0.0001456674,0.01314822,0.3793108,0.0003709983,0.0002137757,0.0001901138],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962924,0.002460859,0.000009054147,0.0003116619,0.0004120182,0.0003103872,0.00004176176,0.00004289719,0.0001189576],"genre_scores_gemma":[0.998964,0.0001149483,0.0002385406,0.0001006658,0.0001633955,0.000006733696,0.0002387977,0.00003583941,0.0001370707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1004065,"threshold_uncertainty_score":0.678692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353702481432531,"score_gpt":0.2405446776307807,"score_spread":0.2270076528164554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}