{"id":"W4395664298","doi":"10.1101/2024.04.25.24306382","title":"<i>Plasmodium knowlesi</i> infection is associated with elevated circulating biomarkers of brain injury and endothelial activation","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Malaria Research and Control","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"London School of Hygiene and Tropical Medicine","keywords":"Plasmodium knowlesi; Malaria; Public health; Plasmodium (life cycle); Medicine; Virology; Immunology; Plasmodium falciparum; Pathology; Parasite hosting; Plasmodium vivax","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401701,0.0002213942,0.0002070092,0.0002441495,0.0002186778,0.0003985569,0.00009803281,0.0002486214,0.001487748],"category_scores_gemma":[0.0005095219,0.0001287602,0.0001268916,0.0001735024,0.0001801446,0.0001832093,0.0002296492,0.0002458118,0.0002083327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604681,"about_ca_system_score_gemma":0.0001303386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009613654,"about_ca_topic_score_gemma":0.0009777523,"domain_scores_codex":[0.9999005,0.00002189771,0.00001269634,0.00002672265,0.00001695393,0.00002122201],"domain_scores_gemma":[0.9995903,0.00003371814,0.0002751224,0.00001952126,0.00004664619,0.00003473387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001830972,0.0001263123,0.934371,0.0002444952,0.0001635552,0.00121605,0.0004144722,0.00009668445,0.04709826,0.00007623088,0.00082121,0.01354067],"study_design_scores_gemma":[0.000007314968,0.0002692967,0.9934151,0.00002012565,0.00003296233,0.0027694,0.0001723175,0.0001193393,0.002734027,0.00003960654,0.0004161646,0.000004286376],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987943,0.0004360155,0.0001097628,0.00004693529,0.000005411466,0.000005445147,0.0001333917,0.000008420477,0.0004603354],"genre_scores_gemma":[0.999286,0.0001529637,0.0001200705,0.00002592488,0.000009655285,0.000004114346,0.0001575717,0.000001301984,0.0002424022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487748,"threshold_uncertainty_score":0.004977047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01830087967819033,"score_gpt":0.2852199006530627,"score_spread":0.2669190209748724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}