{"id":"W4395678220","doi":"10.1016/j.immuni.2024.04.003","title":"CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment","year":2024,"lang":"en","type":"article","venue":"Immunity","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Howard Hughes Medical Institute; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Stars Foundation; University of Chicago; Cancer Research Foundation; V Foundation for Cancer Research; American Association for Cancer Research","keywords":"Biology; Stem cell; Cell biology; CD80; Cancer research; Inflammation; Inflammatory response; Immunology; Genetics; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007351859,0.0002626795,0.0002772845,0.0002313049,0.0001653487,0.00002212404,0.0002095175,0.0003204615,0.0007114074],"category_scores_gemma":[0.000006516408,0.0002379587,0.0001563968,0.0001256595,0.0001652533,0.0002340952,0.0001121032,0.0007178821,0.001829392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001875554,"about_ca_system_score_gemma":0.0001020193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002970431,"about_ca_topic_score_gemma":0.00001544501,"domain_scores_codex":[0.9980292,0.000678547,0.0005585317,0.0003810163,0.00008569629,0.000266948],"domain_scores_gemma":[0.9989075,0.0000997426,0.0001344014,0.0007670823,0.00004466887,0.00004662096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007143313,0.0002542912,0.00001419061,0.00009510464,0.0001044053,0.000004115019,0.003988216,0.0004784858,0.9813837,0.0001373976,0.002284755,0.01054101],"study_design_scores_gemma":[0.0002488456,0.001522841,0.0009425051,0.0002166484,0.00003380677,0.00001147411,0.001922629,0.0002072716,0.9766359,0.00001524371,0.01800811,0.0002346752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949514,0.0003723693,0.0002997078,0.00002770594,0.0033709,0.0003987361,0.00001323747,0.0002412771,0.0003246455],"genre_scores_gemma":[0.9934494,0.00003734941,0.00006383481,0.00009749327,0.00003171474,0.00002793357,0.00004848629,0.00003733116,0.006206496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01572336,"threshold_uncertainty_score":0.9989478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127923178975631,"score_gpt":0.2276283706993112,"score_spread":0.2148360528017481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}