{"id":"W4395691338","doi":"10.1186/s13223-024-00892-w","title":"Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study","year":2024,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Science and Technology Program of Zhejiang Province; Major Scientific and Technological Project of Zhejiang Province; Natural Science Foundation of Zhejiang Province; State Administration of Traditional Chinese Medicine of the People's Republic of China","keywords":"Hay fever; Atopy; Alopecia areata; Allergy; Medicine; Genome-wide association study; Mendelian randomization; Immunology; Genetic predisposition; Asthma; Single-nucleotide polymorphism; Dermatology; Disease; Biology; Genetics; Genotype; Internal medicine; Genetic variants","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886098,0.000256329,0.0007271222,0.0001418312,0.0001164376,0.00005753175,0.000103963,0.0005821469,0.0001794789],"category_scores_gemma":[0.0001922918,0.0002030282,0.0001293474,0.0001780329,0.000300998,0.00009248313,0.0001594876,0.0006662837,0.00007159685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001480545,"about_ca_system_score_gemma":0.000101888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004358412,"about_ca_topic_score_gemma":0.001137715,"domain_scores_codex":[0.9978113,0.0003083891,0.0007688347,0.0006871563,0.0001458491,0.0002784726],"domain_scores_gemma":[0.9986542,0.0006737961,0.00006598425,0.0003234465,0.00006163208,0.0002209596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.008279029,0.002706301,0.2711783,0.00008700819,0.02476947,0.001545454,0.006594982,0.000009783206,0.0005605536,0.003812662,0.002636618,0.6778198],"study_design_scores_gemma":[0.01652808,0.002382969,0.8740023,0.00009481755,0.0002195229,0.00003093211,0.001294878,0.0005070969,0.00001323245,0.002554232,0.1020813,0.0002906226],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719383,0.02354065,0.0008177795,0.001350059,0.0004739439,0.0004697705,0.000009142112,0.0001198866,0.001280493],"genre_scores_gemma":[0.9911021,0.007191951,0.0002453967,0.0004657253,0.0004519678,0.00003343471,0.0001175177,0.00003467464,0.0003572611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6775292,"threshold_uncertainty_score":0.827925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01954347664428693,"score_gpt":0.3072064068282344,"score_spread":0.2876629301839474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}