{"id":"W4395955064","doi":"10.1016/j.scr.2024.103430","title":"Generation of a lymphoblastoid-derived induced pluripotent stem cell line (CBRCULi015-A) from a patient with congenital myotonic dystrophy","year":2024,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"U.S. Department of Defense","keywords":"Myotonic dystrophy; Induced pluripotent stem cell; Biology; Lymphoblast; Mutation; Genetics; Disease; Cell culture; Gene; Cell biology; Embryonic stem cell; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002245768,0.000345929,0.0003309512,0.0004089724,0.0002607973,0.000285832,0.0004911265,0.0001072775,0.0001185734],"category_scores_gemma":[0.00002466403,0.0002822086,0.0001344398,0.0009990928,0.0002969524,0.0001733647,0.0003252899,0.0004427672,0.000222114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002359314,"about_ca_system_score_gemma":0.000888405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001367036,"about_ca_topic_score_gemma":0.00004417029,"domain_scores_codex":[0.9945766,0.001054945,0.0005215482,0.001248908,0.001886082,0.000711861],"domain_scores_gemma":[0.9979582,0.000466331,0.0001171601,0.0007071189,0.0004132534,0.0003379818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002269418,0.0003241806,0.00003122156,0.0001273944,0.00002206947,0.0003483079,0.001312183,0.0009352235,0.9924145,0.00004166408,0.0001660766,0.004050223],"study_design_scores_gemma":[0.0007950283,0.001832793,0.00008270339,0.00006280231,0.0000333394,0.000008799556,0.001005804,0.01288624,0.9827342,0.00001528027,0.0002794456,0.0002635574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956349,0.001123352,0.0002461885,0.0001035258,0.0003584671,0.001291175,0.0003685283,0.00008747086,0.0007864553],"genre_scores_gemma":[0.9984376,0.0001129019,0.0001107081,0.00005805802,0.000150731,0.0002351177,0.0000274849,0.00008845354,0.0007789606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01195102,"threshold_uncertainty_score":0.999963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1116842295121647,"score_gpt":0.3081239068699698,"score_spread":0.196439677357805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}