{"id":"W4396229616","doi":"10.1152/ajpcell.00207.2024","title":"Acute effects of a ketone monoester, whey protein, or their coingestion on mTOR trafficking and protein-protein colocalization in human skeletal muscle","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Colocalization; Skeletal muscle; PI3K/AKT/mTOR pathway; Chemistry; Biochemistry; Cell biology; Biology; Endocrinology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001614074,0.0003207447,0.0003810697,0.0001043858,0.0002200001,0.0002328919,0.0001015924,0.0002258134,0.001361473],"category_scores_gemma":[0.0001326861,0.0001262727,0.0002838082,0.0001483303,0.0003064718,0.0002591684,0.0002494548,0.0004445666,0.0001565369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001615652,"about_ca_system_score_gemma":0.0002374559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007790534,"about_ca_topic_score_gemma":0.001745248,"domain_scores_codex":[0.9998649,0.00002902716,0.00001460848,0.00003410038,0.00001755067,0.00003977073],"domain_scores_gemma":[0.9999043,0.00003234279,0.00001670646,0.000007843245,0.00001094374,0.00002789016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007970916,0.0003444522,0.0007394872,0.0001419266,0.00003202643,0.0001883758,0.00006361871,0.00007744077,0.987137,0.00002068401,0.00005407423,0.00323009],"study_design_scores_gemma":[0.0001195669,0.006668607,0.01275229,0.00001151163,0.00008990873,0.0001927077,0.000171446,0.0004092755,0.9785458,0.00001924946,0.001008718,0.00001101294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978951,0.001476993,0.0002187099,0.00003205036,0.00002347823,0.00001720616,0.0001041652,0.000009039079,0.0002232314],"genre_scores_gemma":[0.9965827,0.001086713,0.001000316,0.00004821116,0.00001853855,0.00005157993,0.0001641257,0.000006584756,0.001041197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001361473,"threshold_uncertainty_score":0.00455451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005236396921874154,"score_gpt":0.2383771817040742,"score_spread":0.2331407847822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}